# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "ADImpute" in publications use:' type: software license: GPL-3.0-only title: 'ADImpute: Adaptive Dropout Imputer (ADImpute)' version: 1.22.0 doi: 10.32614/CRAN.package.ADImpute abstract: 'Single-cell RNA sequencing (scRNA-seq) methods are typically unable to quantify the expression levels of all genes in a cell, creating a need for the computational prediction of missing values (‘dropout imputation’). Most existing dropout imputation methods are limited in the sense that they exclusively use the scRNA-seq dataset at hand and do not exploit external gene-gene relationship information. Here we propose two novel methods: a gene regulatory network-based approach using gene-gene relationships learnt from external data and a baseline approach corresponding to a sample-wide average. ADImpute can implement these novel methods and also combine them with existing imputation methods (currently supported: DrImpute, SAVER). ADImpute can learn the best performing method per gene and combine the results from different methods into an ensemble.' authors: - family-names: Leote given-names: Ana Carolina email: anacarolinaleote@gmail.com orcid: https://orcid.org/0000-0003-0879-328X repository: https://bioc-release.r-universe.dev repository-code: https://github.com/anacarolinaleote/ADImpute commit: b9fcc5fba222fd9a729b87b157d5cffa76b46816 url: https://github.com/anacarolinaleote/ADImpute date-released: '2026-04-28' contact: - family-names: Leote given-names: Ana Carolina email: anacarolinaleote@gmail.com orcid: https://orcid.org/0000-0003-0879-328X