Package 'DLBCL'

Title: Diffuse large B-cell lymphoma expression data
Description: This package provides additional expression data on diffuse large B-cell lymphomas for the BioNet package.
Authors: Marcus Dittrich and Daniela Beisser
Maintainer: Marcus Dittrich <[email protected]>
License: GPL (>=2)
Version: 1.52.0
Built: 2026-10-10 11:16:09 UTC
Source: https://github.com/bioc/DLBCL

Help Index

Routines for the functional analysis of biological networks

Description

This package provides an expression set on diffuse large B-cell lymphoma and an protein-protein interaction network obtained from HPRD release 6. It accompanies the BioNet packages as example data. For further information on the data and the BioNet package, see references below.

Details

Package: DLBCL
Type: Package
Version: 1.2
Date: 2010-03-26
License: GPL (>=2)
LazyLoad: yes

Author(s)

Marcus Dittrich, Daniela Beisser

Maintainer: Marcus Dittrich <[email protected]>

References

M. T. Dittrich, G. W. Klau, A. Rosenwald, T. Dandekar and T. Mueller (2008) Identifying functional modules in protein-protein interaction networks: an integrated exact approach. (ISMB2008) Bioinformatics 24: 13. i223-i231 Jul.

D. Beisser, G. W. Klau, T. Dandekar, T. Mueller and M. Dittrich (2009) BioNet: an R-package for the Functional Analysis of Biological Networks. Bioinformatics.

A. A. Alizadeh, M. B. Eisen, R. E. Davis et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-11.

Additional data for the lymphoma microarray chip (exprLym)

Description

The dataset contains additional data for the exprLym dataset. It includes p-values for the gene expression, p-values for the survival data, an example score etc.

Usage

data(dataLym)

References

A. Rosenwald et al. (2002). The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med, 346(25), 1937-1947.

Examples

data(dataLym)
str(dataLym)

Expression set diffuse large B-cell lymphomas

Description

The dataset contains an expression set on diffuse large B-cell lymphoma. It accompanies the BioNet packages as example data. For further information on the data and the BioNet package see:

M. T. Dittrich, G. W. Klau, A. Rosenwald, T. Dandekar and T. Mueller (2008) Identifying functional modules in protein-protein interaction networks: an integrated exact approach. (ISMB2008) Bioinformatics 24: 13. i223-i231 Jul.

D. Beisser, G. W. Klau, T. Dandekar, T. Mueller and M. Dittrich (2009) BioNet: an R-package for the Functional Analysis of Biological Networks. Bioinformatics.

A. A. Alizadeh, M. B. Eisen, R. E. Davis et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-11.

Usage

data(exprLym)

Examples

data(exprLym)
exprs(exprLym)[1:10,]

Human protein-protein interaction network

Description

The dataset contains the human proteome, extracted from the Human Protein Reference Database (HPRD) from 2006 that is used in the ABC GCB diffuse large B-cell lymphma analysis. The format of the dataset is a graph object.

Usage

data(interactome)

References

M. T. Dittrich, G. W. Klau, A. Rosenwald, T. Dandekar, T. Mueller (2008) Identifying functional modules in protein-protein interaction networks: an integrated exact approach. (ISMB2008) Bioinformatics, 24: 13. i223-i231 Jul.

Examples

data(interactome)
interactome