| Title: | Single-cell RNA-seq datasets of EMT responses from Cook et al. (2020) |
|---|---|
| Description: | Provides 12 single-cell RNA-seq datasets profiling epithelial–mesenchymal transition (EMT) in human cancer cell lines (MCF7, OVCA420, DU145, and A549) under TGF-beta stimulation, kinase inhibition, and time-course conditions, as reported by Cook DP and Vanderhyden BC (2020). The datasets are distributed via ExperimentHub as SingleCellExperiment objects. |
| Authors: | Haimei Wen [aut, cre] (ORCID: <https://orcid.org/0009-0006-1600-1210>), Tian Hong [fnd] |
| Maintainer: | Haimei Wen <[email protected]> |
| License: | GPL-3 |
| Version: | 1.0.0 |
| Built: | 2026-10-10 12:16:18 UTC |
| Source: | https://github.com/bioc/EMTscoreData |
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines A549 treated with EGF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 EGF dataset A549_EGF <- eh[["EH10292"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 EGF dataset A549_EGF <- eh[["EH10292"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines A549 treated with TGFB1
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 TGFB1 dataset A549_TGFB1 <- eh[["EH10293"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 TGFB1 dataset A549_TGFB1 <- eh[["EH10293"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines A549 treated with TNF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 TNF dataset A549_TNF <- eh[["EH10291"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load A549 TNF dataset A549_TNF <- eh[["EH10291"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines DU145 treated with EGF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 EGF dataset DU145_EGF <- eh[["EH10289"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 EGF dataset DU145_EGF <- eh[["EH10289"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines DU145 treated with TGFB1
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 TGFB1 dataset DU145_TGFB1 <- eh[["EH10290"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 TGFB1 dataset DU145_TGFB1 <- eh[["EH10290"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines DU145 treated with TNF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 TNF dataset DU145_TNF <- eh[["EH10288"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load DU145 TNF dataset DU145_TNF <- eh[["EH10288"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines MCF7 treated with EGF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 EGF dataset MCF7_EGF <- eh[["EH10283"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 EGF dataset MCF7_EGF <- eh[["EH10283"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines MCF7 treated with TGFB1
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 TGFB1 dataset MCF7_TGFB1 <- eh[["EH10284"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 TGFB1 dataset MCF7_TGFB1 <- eh[["EH10284"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines MCF7 treated with TNF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 TNF dataset MCF7_TNF <- eh[["EH10282"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load MCF7 TNF dataset MCF7_TNF <- eh[["EH10282"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines OVCA420 treated with EGF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 EGF dataset OVCA420_EGF <- eh[["EH10286"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 EGF dataset OVCA420_EGF <- eh[["EH10286"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines OVCA420 treated with TGFB1
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 TGFB1 dataset OVCA420_TGFB1 <- eh[["EH10287"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 TGFB1 dataset OVCA420_TGFB1 <- eh[["EH10287"]]
The EMTscoreData package provides 12 single-cell RNA-seq datasets from Cook DP, Vanderhyden BC (2020). Context specificity of the EMT transcriptional response. Nature Communications 11(1):2142.
SingleCellExperiment object containing scRNA-seq profiles for cell line and treatment.
These datasets profile epithelial-mesenchymal transition (EMT) in human cancer cell lines OVCA420 treated with TNF
Each dataset was processed into a SingleCellExperiment object and saved as an .rda file.
The datasets can be accessed via ExperimentHub using the provided
accessors. Each object contains gene expression matrices and associated
cell metadata, such as treatment.
SingleCellExperiment dataset
Cook DP, Vanderhyden BC. Context specificity of the EMT transcriptional response. Nature Communications 2020 May 1;11(1):2142.
library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 TNF dataset OVCA420_TNF <- eh[["EH10285"]]library(ExperimentHub) eh <- ExperimentHub() query(eh, "EMTscoreData") #Example: load OVCA420 TNF dataset OVCA420_TNF <- eh[["EH10285"]]