ExpoRiskR

ExpoRiskR is a Bioconductor package for exposure‑aware multi‑omics integration.
It provides a unified framework to quantify exposure perturbation effects, build exposure‑adjusted networks, and derive interpretable risk scores from integrated omics data.

Installation

Install the released version from Bioconductor:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ExpoRiskR")

You can install the development version from GitHub:

if (!requireNamespace("devtools", quietly = TRUE))
    install.packages("devtools")

devtools::install_github("ppchaudhary/ExpoRiskR")

Overview

ExpoRiskR enables:

The package is designed to work seamlessly with Bioconductor data structures such as SummarizedExperiment.

Quick Example

library(ExpoRiskR)

# Generate example data
data <- generate_dummy_exporisk()

# Align omics data
aligned <- align_omics(
  data$omics,
  data$metadata,
  exposure_col = "exposure"
)

# Compute exposure perturbation score
scores <- compute_exposure_scores(aligned)

# Build exposure‑adjusted network
net <- build_exposure_network(scores)

plot_network(net)

Documentation

Full tutorials and workflow examples are available in the package vignette:

browseVignettes("ExpoRiskR")

Citation

If you use ExpoRiskR in your research, please cite:

Chaudhary PP et al. ExpoRiskR: Exposure‑aware multi‑omics risk modeling framework.

Support

For questions, issues, or feature requests: