Package 'FIs'

Title: Human Functional Interactions (FIs) for splineTimeR package
Description: Data set containing two complete lists of identified functional interaction partners in Human. Data are derived from Reactome and BioGRID databases.
Authors: Agata Michna
Maintainer: Herbert Braselmann <[email protected]>, Martin Selmansberger <[email protected]>
License: GPL-3
Version: 1.40.0
Built: 2026-10-10 11:07:20 UTC
Source: https://github.com/bioc/FIs

Help Index

Human Functional Interactions (FIs)

Description

Data set with two complete lists of identified functional interaction partners in Human. Data are derived from Reactome and BioGRID databases.

Usage

data(FIs)

Format

A list of two data frames with two columns describing interaction partners.

FIs_Reactome

functional interactions derived from Reactome database

FIs_BioGRID

functional interactions derived from BioGRID database

Details

The data sets contain unique interaction pairs. Self-loops are not considered.

Value

A list of two data frames.

Source

Reactome functional interaction pairs. Retrieved December 3, 2015 from http://www.reactome.org/pages/download-data/

BioGRID functional interaction pairs. Retrieved December 3, 2015 from http://thebiogrid.org/download.php

References

Croft, D., Mundo, A. F., Haw R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., Hermjakob, H., Stein, L., D'Eustachio, P. (2014). The Reactome pathway knowledgebase. Nucleic Acids Research 42(Database issue), 472-477.

Stark, C., Breitkreutz, B.-J., Reguly, T. Boucher, L., Breitkreutz, A., Tyers, M. (2006). BioGRID: a general repository for interaction datasets. Nucleic Acids Research 34(Database issue), 535-539.

Examples

data(FIs)
names(FIs)
head(FIs$FIs_Reactome)
head(FIs$FIs_BioGRID)