Description | Differential expression analysis | E2 and FGFR2 signatures | Principal components analysis | Follow-up on differentially expressed genes | Session information
Package: Fletcher2013a 1.48.0
Mauro Castro
Fletcher2013a: Gene expression data from breast cancer cells under FGFR2 signalling perturbation
The package Fletcher2013a contains time-course gene expression data from MCF-7 cells treated under different experimental systems in order to perturb FGFR2 signalling. The data comes from Fletcher et al. (Nature Comms 4:2464, 2013) where further details about the background and the experimental design of the study can be found.
Authors:
Fletcher2013a_1.48.0.tar.gz
Fletcher2013a_1.48.0.tar.gz(r-4.7-any)Fletcher2013a_1.48.0.tar.gz(r-4.6-any)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
Fletcher2013a/json (API)
| # Install 'Fletcher2013a' in R: |
| install.packages('Fletcher2013a', repos = c('https://bioc-release.r-universe.dev', 'https://cloud.r-project.org')) |
Datasets:
- Exp1 - Exp1 dataset: endogenous FGFRs experiments.
- Exp1limma - Exp1 dataset: endogenous FGFRs experiments.
- Exp2 - Exp2 dataset: iF2 construct experiments.
- Exp2limma - Exp2 dataset: iF2 construct experiments.
- Exp3 - Exp3 dataset: FGFR2b over-expression experiments.
- Exp3limma - Exp3 dataset: FGFR2b over-expression experiments.
- siESR1 - Knockdown dataset: siESR1 in MCF-7 cells.
- siESR1limma - Knockdown dataset: siESR1 in MCF-7 cells.
- siOTHERS - Knockdown dataset: siPTTG1, siSPDEF, siE2F2 and siELF3 in MCF-7 cells.
- siOTHERSlimma - Knockdown dataset: siPTTG1, siSPDEF, siE2F2 and siELF3 in MCF-7 cells.
On BioConductor:Fletcher2013a-1.49.0(data/experiment 3.24)Fletcher2013a-1.48.0(data/experiment 3.23)
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
experimentdataexpressiondatacancerdatabreastcancerdatamicroarraydatadatapkg
Last updated from:c790679cb1 (on RELEASE_3_23). Checks:1 FAILURE, 3 OK. Indexed: no.
This is a data package. Data packages may be large and do not get checked across all platforms.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| bioc-checks | FAILURE | 124 | ||
| linux-devel | OK | 179 | ||
| source / vignettes | OK | 278 | ||
| linux-release | OK | 143 |
Exports:Fletcher2013pipeline.degFletcher2013pipeline.limmaFletcher2013pipeline.pcaFletcher2013pipeline.supp
Dependencies:BiobaseBiocGenericsbitopscaToolsformatRfutile.loggerfutile.optionsgenericsgplotsgtoolsKernSmoothlambda.rlimmastatmodVennDiagram
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Exp1 dataset: endogenous FGFRs experiments. | Exp1 Exp1limma Fletcher2013a |
| Exp2 dataset: iF2 construct experiments. | Exp2 Exp2limma |
| Exp3 dataset: FGFR2b over-expression experiments. | Exp3 Exp3limma |
| A pipeline to reproduce results for Fletcher et al. 2013. | Fletcher2013pipeline.deg Fletcher2013pipeline.limma Fletcher2013pipeline.pca Fletcher2013pipeline.supp |
| Knockdown dataset: siESR1 in MCF-7 cells. | siESR1 siESR1limma |
| Knockdown dataset: siPTTG1, siSPDEF, siE2F2 and siELF3 in MCF-7 cells. | siOTHERS siOTHERSlimma |
