| Title: | Illumina HumanMethylation data on sorted frontal cortex cell populations |
|---|---|
| Description: | Raw data objects for the Illumina 450k DNA methylation microarrays. |
| Authors: | Andrew E Jaffe, Zachary A. Kaminsky |
| Maintainer: | Andrew E Jaffe <[email protected]> |
| License: | Artistic-2.0 |
| Version: | 1.48.0 |
| Built: | 2026-10-10 11:06:38 UTC |
| Source: | https://github.com/bioc/FlowSorted.DLPFC.450k |
This RGChannelSet contains Illumina 450k DNA methylation
measurements on 58 flow-sorted dorsolateral prefrontal cortex samples
from non-psychiatric controls from Guintivano et al. 2013. These
samples were separated into neuronal (NeuN+) and non-neuronal (NeuN-)
cell types. These data can be used by the minfi package to
estimate cellular composition from bulk frontal cortex samples. This
data may also be useful to individuals as example Illumina 450k data
for trying preprocessing methods across a variety of Bioconductor
packages.
data(FlowSorted.DLPFC.450k)data(FlowSorted.DLPFC.450k)
An object of class RGChannelSet.
The FlowSorted.DLPFC.450k objects is based an samples assayed
as part of Guintivano et al (2013). Please cite this paper, if the
data is used. If you're using this data together with the
minfi package, please see the package vignette for details on
how to cite that package.
Guintivano J., Aryee M.J., Kaminsky Z.A. A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics (2013), 8(3):290-302. doi:10.4161/epi.23924.
data(FlowSorted.DLPFC.450k)data(FlowSorted.DLPFC.450k)