Package: LegATo Title: LegATo: Longitudinal mEtaGenomic Analysis Toolkit Version: 1.6.0 Authors@R: c( person("Aubrey", "Odom", , "aodom@bu.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-7113-7598")), person("Yilong", "Zhang", , "elong0527@gmail.com", role = "ctb", comment = "Author of NMIT functions"), person("Jared", "Pincus", , "pincus@bu.edu", role = "csl", comment = c(ORCID = "0000-0001-6708-5262", other = "Naming consultant of package")), person("Jordan", "Pincus", , "pincus@bu.edu", role = "art", comment = "Artist of LegATo icon") ) Description: LegATo is a suite of open-source software tools for longitudinal microbiome analysis. It is extendable to several different study forms with optimal ease-of-use for researchers. Microbiome time-series data presents distinct challenges including complex covariate dependencies and variety of longitudinal study designs. This toolkit will allow researchers to determine which microbial taxa are affected over time by perturbations such as onset of disease or lifestyle choices, and to predict the effects of these perturbations over time, including changes in composition or stability of commensal bacteria. License: MIT + file LICENSE URL: https://wejlab.github.io/LegATo-docs/ BugReports: https://github.com/wejlab/LegATo/issues Depends: R (>= 4.4.0) Imports: animalcules, data.table, dplyr, ggplot2, magrittr, MultiAssayExperiment, plyr, rlang, S4Vectors, stringr, SummarizedExperiment, tibble, tidyr, tidyselect Suggests: BiocStyle, broom, broom.mixed, circlize, ComplexHeatmap, emmeans, geepack, ggalluvial, ggeffects, grDevices, knitr, lme4, lmerTest, methods, RColorBrewer, rmarkdown, spelling, TBSignatureProfiler, testthat (>= 3.0.0), TreeSummarizedExperiment, usethis, vegan VignetteBuilder: knitr BiocType: Software biocViews: MicrobiomeData, ReproducibleResearch, SequencingData Config/testthat/edition: 3 Encoding: UTF-8 Language: en-US RoxygenNote: 7.3.2 Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:37:40 UTC RemoteUrl: https://github.com/bioc/LegATo RemoteRef: RELEASE_3_23 RemoteSha: b9eabb97ebf21b1d9ef6a2ca7412a4a2ae86a811 NeedsCompilation: no Packaged: 2026-10-10 11:20:37 UTC; root Author: Aubrey Odom [aut, cre] (ORCID: ), Yilong Zhang [ctb] (Author of NMIT functions), Jared Pincus [csl] (ORCID: , other: Naming consultant of package), Jordan Pincus [art] (Artist of LegATo icon) Maintainer: Aubrey Odom