Package: RAREsim Version: 1.16.0 Date: 2020-08-01 Title: Simulation of Rare Variant Genetic Data Description: Haplotype simulations of rare variant genetic data that emulates real data can be performed with RAREsim. RAREsim uses the expected number of variants in MAC bins - either as provided by default parameters or estimated from target data - and an abundance of rare variants as simulated HAPGEN2 to probabilistically prune variants. RAREsim produces haplotypes that emulate real sequencing data with respect to the total number of variants, allele frequency spectrum, haplotype structure, and variant annotation. Authors@R: c(person(given = "Megan", family = "Null", role = "aut", email = "mnull@collegeofidaho.edu"), person(given = "Ryan", family = "Barnard", role = "cre", email = "rbarnard1107@gmail.com")) URL: https://github.com/meganmichelle/RAREsim BugReports: https://github.com/meganmichelle/RAREsim/issues License: GPL-3 LazyData: FALSE biocViews: Genetics, Software, VariantAnnotation, Sequencing RoxygenNote: 7.1.2 Encoding: UTF-8 VignetteBuilder: knitr Depends: R (>= 4.1.0) Imports: nloptr Suggests: markdown, ggplot2, BiocStyle, rmarkdown, knitr, testthat (>= 3.0.0) Config/testthat/edition: 3 Config/pak/sysreqs: cmake Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:58:22 UTC RemoteUrl: https://github.com/bioc/RAREsim RemoteRef: RELEASE_3_23 RemoteSha: a37e532b1089569a46ff04578debf3bb5deeaff6 NeedsCompilation: no Packaged: 2026-07-25 07:44:55 UTC; root Author: Megan Null [aut], Ryan Barnard [cre] Maintainer: Ryan Barnard