# --------------------------------------------
# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "RTN" in publications use:'
type: software
license: Artistic-2.0
title: 'RTN: RTN: Reconstruction of Transcriptional regulatory Networks and analysis
  of regulons'
version: 2.36.0
doi: 10.1038/ng.3458
identifiers:
- type: doi
  value: 10.32614/CRAN.package.RTN
abstract: A transcriptional regulatory network (TRN) consists of a collection of transcription
  factors (TFs) and the regulated target genes. TFs are regulators that recognize
  specific DNA sequences and guide the expression of the genome, either activating
  or repressing the expression the target genes. The set of genes controlled by the
  same TF forms a regulon. This package provides classes and methods for the reconstruction
  of TRNs and analysis of regulons.
authors:
- family-names: Castro
  given-names: Mauro
  email: mauro.a.castro@gmail.com
- family-names: Wang
  given-names: Xin
- family-names: Fletcher
  given-names: Michael
- family-names: Markowetz
  given-names: Florian
- family-names: Meyer
  given-names: Kerstin
preferred-citation:
  type: article
  title: Regulators of genetic risk of breast cancer identified by integrative network
    analysis.
  authors:
  - family-names: Castro
    given-names: Mauro
    email: mauro.a.castro@gmail.com
  - family-names: Santiago
    given-names: Ines
    name-particle: de
  - family-names: Campbell
    given-names: Thomas
  - family-names: Vaughn
    given-names: Courtney
  - family-names: Hickey
    given-names: Theresa
  - family-names: Ross
    given-names: Edith
  - family-names: Tilley
    given-names: Wayne
  - family-names: Markowetz
    given-names: Florian
  - family-names: Ponder
    given-names: Bruce
  - family-names: Meyer
    given-names: Kerstin
  journal: Nature Genetics
  year: '2016'
  volume: '48'
  doi: 10.1038/ng.3458
  start: '33'
repository: https://bioc-release.r-universe.dev
commit: 451bf4e651589695891b5ba3947572a6f25ccfd2
url: http://dx.doi.org/10.1038/ncomms3464
date-released: '2026-04-28'
contact:
- family-names: Castro
  given-names: Mauro
  email: mauro.a.castro@gmail.com
references:
- type: article
  title: Master regulators of FGFR2 signalling and breast cancer risk.
  authors:
  - family-names: Fletcher
    given-names: Michael
  - family-names: Castro
    given-names: Mauro
  - family-names: Wang
    given-names: Xin
  - family-names: Santiago
    given-names: Ines
    name-particle: de
  - family-names: O'Reilly
    given-names: Martin
  - family-names: Chin
    given-names: Suet-Feung
  - family-names: Rueda
    given-names: Oscar
  - family-names: Caldas
    given-names: Carlos
  - family-names: Ponder
    given-names: Bruce
  - family-names: Markowetz
    given-names: Florian
  - family-names: Meyer
    given-names: Kerstin
  journal: Nature Communications
  year: '2013'
  volume: '4'
  doi: 10.1038/ncomms3464
  start: '2464'