Package: VERSO Version: 1.22.0 Date: 2026-03-09 Title: Viral Evolution ReconStructiOn (VERSO) Authors@R: c(person("Daniele", "Ramazzotti", role=c("aut"),email="daniele.ramazzotti@unimib.it", comment = c(ORCID = "0000-0002-6087-2666")), person("Fabrizio","Angaroni",role=c("aut"),email="fabrizio.angaroni@unimib.it"), person("Davide","Maspero",role=c("cre","aut"),email="d.maspero@campus.unimib.it"), person("Alex","Graudenzi",role=c("aut"),email="alex.graudenzi@unimib.it"), person("Luca", "De Sano", role=c("aut"), email="luca.desano@gmail.com", comment = c(ORCID = "0000-0002-9618-3774"))) Depends: R (>= 4.1.0) Imports: utils, data.tree, ape, parallel, Rfast, stats Suggests: BiocGenerics, BiocStyle, testthat, knitr Name: VERSO: an R package for the inference of viral evolution models Description: Mutations that rapidly accumulate in viral genomes during a pandemic can be used to track the evolution of the virus and, accordingly, unravel the viral infection network. To this extent, sequencing samples of the virus can be employed to estimate models from genomic epidemiology and may serve, for instance, to estimate the proportion of undetected infected people by uncovering cryptic transmissions, as well as to predict likely trends in the number of infected, hospitalized, dead and recovered people. VERSO is an algorithmic framework that processes variants profiles from viral samples to produce phylogenetic models of viral evolution. The approach solves a Boolean Matrix Factorization problem with phylogenetic constraints, by maximizing a log-likelihood function. VERSO includes two separate and subsequent steps; in this package we provide an R implementation of VERSO STEP 1. Encoding: UTF-8 License: file LICENSE URL: https://github.com/BIMIB-DISCo/VERSO BugReports: https://github.com/BIMIB-DISCo/VERSO biocViews: BiomedicalInformatics, Sequencing, SomaticMutation RoxygenNote: 7.3.3 VignetteBuilder: knitr Config/pak/sysreqs: make libicu-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:54:15 UTC RemoteUrl: https://github.com/bioc/VERSO RemoteRef: RELEASE_3_23 RemoteSha: 68c974c5925c5f32d57386a4e39d38d33fa54cba NeedsCompilation: no Packaged: 2026-07-03 23:58:52 UTC; root Author: Daniele Ramazzotti [aut] (ORCID: ), Fabrizio Angaroni [aut], Davide Maspero [cre, aut], Alex Graudenzi [aut], Luca De Sano [aut] (ORCID: ) Maintainer: Davide Maspero