{
  "_id": "6a339fd03efcd9bda43a81c8",
  "Package": "CNORfeeder",
  "Type": "Package",
  "Title": "Integration of CellNOptR to add missing links",
  "Version": "1.52.0",
  "Author": "Federica Eduati [aut, cre]",
  "Maintainer": "Attila Gabor <attila.gabor@uni-heidelberg.de>",
  "Description": "This package integrates literature-constrained and\ndata-driven methods to infer signalling networks from\nperturbation experiments. It permits to extends a given network\nwith links derived from the data via various inference methods\nand uses information on physical interactions of proteins to\nguide and validate the integration of links.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "LazyData": "true",
  "Date": "2022-05-11",
  "Authors@R": "c(\nperson(given = \"Federica\",\nfamily = \"Eduati\",\nrole = \"aut\"),\nperson(given = \"Enio\",\nfamily = \"Gjerga\",\nrole = \"ctb\"),\nperson(given = \"Attila\",\nfamily = \"Gabor\",\nrole = \"cre\",\nemail = \"attila.gabor@uni-heidelberg.de\")\n)",
  "biocViews": "CellBasedAssays, CellBiology, Proteomics, NetworkInference",
  "LazyLoad": "yes",
  "RoxygenNote": "7.1.2",
  "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libuv1-dev\nlibxml2-dev zlib1g-dev",
  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 12:37:30 UTC",
  "RemoteUrl": "https://github.com/bioc/CNORfeeder",
  "RemoteRef": "RELEASE_3_23",
  "RemoteSha": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-06-18 07:16:13 UTC",
    "User": "root"
  },
  "MD5sum": "514939d630907722e0eba7143d5d33af",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "CNORfeeder_1.52.0.tar.gz",
  "_fileid": "3eb67d472f2c78fd79847949bdb660cbb706e77b0ba0c58054281e92a3618622",
  "_filesize": 3604713,
  "_sha256": "3eb67d472f2c78fd79847949bdb660cbb706e77b0ba0c58054281e92a3618622",
  "_created": "2026-06-18T07:16:13.000Z",
  "_published": "2026-06-18T07:35:44.149Z",
  "_jobs": [
    {
      "job": 82075284322,
      "time": 183,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7716645705"
    },
    {
      "job": 82075284300,
      "time": 247,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7716665410"
    },
    {
      "job": 82075284340,
      "time": 250,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7716666899"
    },
    {
      "job": 82075284292,
      "time": 164,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7716941437"
    },
    {
      "job": 82075284299,
      "time": 128,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7716930573"
    },
    {
      "job": 82074724172,
      "time": 220,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7716589039"
    },
    {
      "job": 82075284271,
      "time": 136,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7716631841"
    },
    {
      "job": 82075284293,
      "time": 149,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7716636011"
    },
    {
      "job": 82075284310,
      "time": 120,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7716627179"
    },
    {
      "job": 82075284323,
      "time": 144,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7716634350"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 6,
    "note": 17
  },
  "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/CNORfeeder",
  "_commit": {
    "id": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
    "time": 1777379850
  },
  "_maintainer": {
    "name": "Attila Gabor",
    "email": "attila.gabor@uni-heidelberg.de",
    "login": "gabora",
    "linkedin": "in/attila-g%C3%A1bor-94910524",
    "twitter": "@attila_gbr",
    "description": "Senior Comp-Bio scientist crafting R/Python code for comp. molecular biology/oncology, dedicated to advance healthcare with bioinformatics solutions",
    "uuid": 3891745
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.0.0",
      "role": "Depends"
    },
    {
      "package": "graph",
      "role": "Depends"
    },
    {
      "package": "CellNOptR",
      "version": ">= 1.4.0",
      "role": "Imports"
    },
    {
      "package": "minet",
      "role": "Suggests"
    },
    {
      "package": "Rgraphviz",
      "role": "Suggests"
    },
    {
      "package": "RUnit",
      "role": "Suggests"
    },
    {
      "package": "BiocGenerics",
      "role": "Suggests"
    },
    {
      "package": "igraph",
      "role": "Suggests"
    },
    {
      "package": "MEIGOR",
      "role": "Enhances"
    }
  ],
  "_owner": "bioc",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 1
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.53.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.52.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "cellbasedassays",
    "cellbiology",
    "proteomics",
    "networkinference"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "followers": 440,
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_mentions": 2,
  "_searchresults": 14,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/CNORfeeder.html",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "Binference",
    "buildFeederObjectDynamic",
    "gaBinaryT1W",
    "identifyMisfitIndices",
    "integrateLinks",
    "linksRanking",
    "makeBTables",
    "mapBTables2model",
    "mapDDN2model",
    "MIinference",
    "runDynamicFeeder",
    "weighting"
  ],
  "_datasets": [
    {
      "name": "cnolist",
      "title": "CNOlist",
      "object": "ToyModelPBCNOlist",
      "class": [
        "CNOlist"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "CNOlistToy_Gene",
      "title": "",
      "object": "CNOlistToy_Gene",
      "class": [
        "CNOlist"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "database",
      "title": "OmniPath PPI",
      "object": "database",
      "class": [
        "matrix",
        "array"
      ],
      "fields": {},
      "rows": 12336,
      "table": true,
      "tojson": true
    },
    {
      "name": "feederObject",
      "title": "Feeder Object",
      "object": "feederObject_toy",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "indices",
      "title": "Mis-fit indices",
      "object": "indices",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "integratedModel",
      "title": "Integrated Model",
      "object": "integratedModel_toy",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "model",
      "title": "Prior Knowledge Network",
      "object": "ToyModelPB",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "model",
      "title": "Prior Knowledge Network",
      "object": "ToyModel_Gene",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "PPINigraph",
      "title": "Protein-protein interaction netwrok",
      "object": "PPINigraph",
      "class": [
        "igraph"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "simData",
      "title": "CNORode simuation data",
      "object": "simData_toy",
      "class": [
        "list"
      ],
      "fields": [],
      "table": true,
      "tojson": true
    },
    {
      "name": "UniprotIDdream",
      "title": "Uniprot identifiers for proteins in DreamModel",
      "object": "UniprotIDdream",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "CNORfeeder-package",
      "title": "R package to integrate literature-constrained and data-driven methods to infer signalling networks from perturbation experiments",
      "topics": [
        "CNORfeeder-package",
        "CNORfeeder"
      ]
    },
    {
      "page": "Binference",
      "title": "Bayesian network inference",
      "topics": [
        "Binference"
      ]
    },
    {
      "page": "buildFeederObjectDynamic",
      "title": "Building Feeder-Object for the integration to the PKN",
      "topics": [
        "buildFeederObjectDynamic"
      ]
    },
    {
      "page": "cnolist",
      "title": "CNOlist",
      "topics": [
        "cnolist"
      ]
    },
    {
      "page": "database",
      "title": "OmniPath PPI",
      "topics": [
        "database"
      ]
    },
    {
      "page": "feederObject",
      "title": "Feeder Object",
      "topics": [
        "feederObject"
      ]
    },
    {
      "page": "gaBinaryT1W",
      "title": "Genetic algorithm used to optimise a model differently weighting links",
      "topics": [
        "gaBinaryT1W"
      ]
    },
    {
      "page": "identifyMisfitIndices",
      "title": "Identifying indices of poorly fitted measurements",
      "topics": [
        "identifyMisfitIndices"
      ]
    },
    {
      "page": "indices",
      "title": "Mis-fit indices",
      "topics": [
        "indices"
      ]
    },
    {
      "page": "integratedModel",
      "title": "Integrated Model",
      "topics": [
        "integratedModel"
      ]
    },
    {
      "page": "integrateLinks",
      "title": "Integrating the new links to the PKN",
      "topics": [
        "integrateLinks"
      ]
    },
    {
      "page": "linksRanking",
      "title": "Ranking of links inferred from data",
      "topics": [
        "linksRanking"
      ]
    },
    {
      "page": "makeBTables",
      "title": "Make Boolean tables",
      "topics": [
        "makeBTables"
      ]
    },
    {
      "page": "mapBTables2model",
      "title": "Integrate Boolean tables with the model",
      "topics": [
        "mapBTables2model"
      ]
    },
    {
      "page": "mapDDN2model",
      "title": "Integrate data-drive network with the model",
      "topics": [
        "mapDDN2model"
      ]
    },
    {
      "page": "MIinference",
      "title": "Mutual information based network inference",
      "topics": [
        "MIinference"
      ]
    },
    {
      "page": "model",
      "title": "Prior Knowledge Network",
      "topics": [
        "model"
      ]
    },
    {
      "page": "PPINigraph",
      "title": "Protein-protein interaction netwrok",
      "topics": [
        "PPINigraph"
      ]
    },
    {
      "page": "runDynamicFeeder",
      "title": "Modelling the integrated PKN with CNORode",
      "topics": [
        "runDynamicFeeder"
      ]
    },
    {
      "page": "simData",
      "title": "CNORode simuation data",
      "topics": [
        "simData"
      ]
    },
    {
      "page": "UniprotIDdream",
      "title": "Uniprot identifiers for proteins in DreamModel",
      "topics": [
        "UniprotIDdream"
      ]
    },
    {
      "page": "weighting",
      "title": "Weight integrated links.",
      "topics": [
        "weighting"
      ]
    }
  ],
  "_rundeps": [
    "base64enc",
    "BH",
    "BiocGenerics",
    "bitops",
    "bslib",
    "cachem",
    "CellNOptR",
    "cli",
    "cpp11",
    "digest",
    "evaluate",
    "farver",
    "fastmap",
    "fontawesome",
    "fs",
    "generics",
    "ggplot2",
    "glue",
    "graph",
    "gtable",
    "highr",
    "htmltools",
    "igraph",
    "isoband",
    "jquerylib",
    "jsonlite",
    "knitr",
    "labeling",
    "lattice",
    "lifecycle",
    "magrittr",
    "Matrix",
    "memoise",
    "mime",
    "pkgconfig",
    "R6",
    "rappdirs",
    "RBGL",
    "RColorBrewer",
    "RCurl",
    "Rgraphviz",
    "rlang",
    "rmarkdown",
    "S7",
    "sass",
    "scales",
    "stringi",
    "stringr",
    "tinytex",
    "vctrs",
    "viridisLite",
    "withr",
    "xfun",
    "XML",
    "yaml"
  ],
  "_vignettes": [
    {
      "source": "CNORfeeder-vignette.Rnw",
      "filename": "CNORfeeder-vignette.pdf",
      "title": "Main vignette:Playing with networks using CNORfeeder",
      "engine": "utils::Sweave",
      "headings": [
        "Overview",
        "Installation",
        "Introduction",
        "Example",
        "Dynamic Feeder"
      ],
      "created": "2013-11-01 20:29:42",
      "modified": "2025-03-17 15:21:05",
      "commits": 6
    }
  ],
  "_score": 3.7481880270062007,
  "_indexed": false,
  "_nocasepkg": "cnorfeeder",
  "_universes": [
    "bioc-release"
  ],
  "_indexurl": "https://bioc.r-universe.dev/CNORfeeder",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.52.0",
      "date": "2026-06-18T07:19:51.000Z",
      "distro": "noble",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "332e7ad1dcc87cfc707fcf44748422a1de787e18191beb6bfc43c9ba3b9ce492",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.52.0",
      "date": "2026-06-18T07:20:01.000Z",
      "distro": "noble",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "7e9d5b94cdcb5e8714d31bca6c8cc823a1e529d9b2a3683463003b8ffd5b7e31",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.52.0",
      "date": "2026-06-18T07:34:34.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "6006c7925e64f1b14459d2b2ac1508f126f0a292e44c73298e84e14d839850d9",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.52.0",
      "date": "2026-06-18T07:34:05.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "839d0f8b69bd6aea43073908078d25ed999ebaf52190f4640a5d1fa1cdc55d51",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.52.0",
      "date": "2026-06-18T07:18:51.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "ec7614f55af2fb940491d837d3366c5db9f1e38b727a18a47722627fe603dba8",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.52.0",
      "date": "2026-06-18T07:18:15.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "18306f0983e293541b982edbc7c74cbbe3d2d9f2980b5a327401461159342353",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.52.0",
      "date": "2026-06-18T07:17:46.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "11b0a8bc93918531e63e233f551c422594a376916f783d96618a86fd3ff18c9d",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.52.0",
      "date": "2026-06-18T07:18:06.000Z",
      "commit": "0011363706a70fbce42289e08a3f0b194f6bb2c0",
      "fileid": "427a1cf5c030f6a191ced7a5936168f1e86135947f1640d6bd9a7ec72d627103",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/27743058544"
    }
  ]
}