{
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  "Title": "Exposure-Aware Multi-Omics Risk Modeling",
  "Version": "1.0.0",
  "Authors@R": "c(\nperson(\"Prem Prashant\", \"Chaudhary\",\nemail = \"chaudharyp2@nih.gov\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0002-3467-8608\"))\n)",
  "Description": "ExpoRiskR provides tools for exposure-aware multi-omics\nrisk modeling in translational and environmental health\nstudies. The package aligns sample identifiers across exposure\nand multi-omics blocks, performs lightweight preprocessing, and\nfits exposure-adjusted association models to build\ninterpretable microbe–metabolite networks. It also computes\nsimple exposure perturbation summaries and generates\npublication-ready visualizations. Workflows support both\nmatrix-based inputs and SummarizedExperiment objects.",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.3.2",
  "URL": "https://github.com/ppchaudhary/ExpoRiskR",
  "BugReports": "https://github.com/ppchaudhary/ExpoRiskR/issues",
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  "Config/testthat/edition": "3",
  "biocViews": "Software, Network, SystemsBiology, Metabolomics, Microbiome,\nRegression",
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  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 13:06:43 UTC",
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    "User": "root"
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  "Author": "Prem Prashant Chaudhary [aut, cre] (ORCID:\n<https://orcid.org/0000-0002-3467-8608>)",
  "Maintainer": "Prem Prashant Chaudhary <chaudharyp2@nih.gov>",
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    "network",
    "systemsbiology",
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    "align_omics_se",
    "build_exposure_network",
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    "generate_dummy_exporisk",
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    {
      "page": "align_omics",
      "title": "Align exposures and multi-omics blocks by sample ID",
      "topics": [
        "align_omics"
      ]
    },
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      "page": "align_omics_se",
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        "align_omics_se"
      ]
    },
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      "page": "build_exposure_network",
      "title": "Build an exposure-adjusted microbe-metabolite association network",
      "topics": [
        "build_exposure_network"
      ]
    },
    {
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      "title": "Score exposures by network perturbation (leave-one-exposure-out)",
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        "exposure_perturbation_score"
      ]
    },
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      "page": "generate_dummy_exporisk",
      "title": "Generate simulated exposure + multi-omics data with a binary outcome",
      "topics": [
        "generate_dummy_exporisk"
      ]
    },
    {
      "page": "plot_exposure_network",
      "title": "Plot exposure-adjusted multi-omics network (bipartite)",
      "topics": [
        "plot_exposure_network"
      ]
    },
    {
      "page": "plot_exposure_ranking",
      "title": "Plot exposure perturbation ranking",
      "topics": [
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      ]
    },
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      "page": "plot_feature_importance",
      "title": "Plot feature importance for exposures (logistic regression)",
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    },
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      "page": "plot_individual_risk_profile",
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    },
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      "engine": "knitr::rmarkdown",
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        "Introduction and Motivation",
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        "Related Bioconductor Packages and Comparison",
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