{ "_id": "6aacebbe3d719c1f8407302b", "Package": "HybridMTest", "Type": "Package", "Title": "Hybrid Multiple Testing", "Version": "1.56.0", "Date": "2011-06-14", "Author": "Stan Pounds , Demba Fofana\n", "Maintainer": "Demba Fofana ", "Description": "Performs hybrid multiple testing that incorporates method\nselection and assumption evaluations into the analysis using\nempirical Bayes probability (EBP) estimates obtained by\nGrenander density estimation. For instance, for 3-group\ncomparison analysis, Hybrid Multiple testing considers EBPs as\nweighted EBPs between F-test and H-test with EBPs from Shapiro\nWilk test of normality as weigth. Instead of just using EBPs\nfrom F-test only or using H-test only, this methodology\ncombines both types of EBPs through EBPs from Shapiro Wilk test\nof normality. This methodology uses then the law of total EBPs.", "License": "GPL Version 2 or later", "LazyLoad": "yes", "Packaged": { "Date": "2026-09-18 07:00:22 UTC", "User": "root" }, "biocViews": "GeneExpression, Genetics, Microarray", "Repository": "Bioconductor 3.23", "Date/Publication": "2026-04-28 12:36:21 UTC", "RemoteUrl": "https://github.com/bioc/HybridMTest", "RemoteRef": "RELEASE_3_23", "RemoteSha": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "NeedsCompilation": "no", "_user": "bioc-release", "_type": "src", "_file": "HybridMTest_1.56.0.tar.gz", "_fileid": "https://r2.ropensci.org/3236a6c9948c574128c802e3e45f61f3f862ef806d8f04b3c4f5eba9cbc5c1f9", "_filesize": 294061, "_sha256": "3236a6c9948c574128c802e3e45f61f3f862ef806d8f04b3c4f5eba9cbc5c1f9", "_expires": "2026-12-27T07:43:56.000Z", "_created": "2026-09-18T07:00:22.000Z", "_published": "2026-09-18T07:43:58.385Z", "_bioccheck": { "error": 1, "warning": 3, "note": 13 }, "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578", "_status": "success", "_upstream": "https://github.com/bioc/HybridMTest", "_commit": { "id": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "author": "A Wokaty ", "committer": "A Wokaty ", "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n", "time": 1777379781 }, "_maintainer": { "name": "Demba Fofana", "email": "demba.fofana@stjude.org" }, "_distro": "resolute", "_jobs": [ { "job": 105512048731, "time": 139, "config": "bioc-checks", "r": "4.6.1", "check": "ERROR", "artifact": "10535344012" }, { "job": 105512048748, "time": 202, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "NOTE", "artifact": "10535633998" }, { "job": 105512048790, "time": 159, "config": "linux-release-x86_64", "r": "4.6.1", "check": "NOTE", "artifact": "10535752361" }, { "job": 105512048689, "time": 82, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "NOTE", "artifact": "10536772266" }, { "job": 105512048737, "time": 116, "config": "macos-release-arm64", "r": "4.6.1", "check": "NOTE", "artifact": "10536499449" }, { "job": 105511310257, "time": 185, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "10534858058" }, { "job": 105512048749, "time": 115, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "10535917205" }, { "job": 105512048761, "time": 74, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "NOTE", "artifact": "10535047873" }, { "job": 105512048762, "time": 88, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "NOTE", "artifact": "10535377637" }, { "job": 105512048711, "time": 84, "config": "windows-release-x86_64", "r": "4.6.1", "check": "NOTE", "artifact": "10534964416" } ], "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 2.9.0", "role": "Depends" }, { "package": "Biobase", "role": "Depends" }, { "package": "fdrtool", "role": "Depends" }, { "package": "MASS", "role": "Depends" }, { "package": "survival", "role": "Depends" }, { "package": "stats", "role": "Imports" } ], "_owner": "bioc", "_selfowned": false, "_usedby": 0, "_updates": [ { "week": "2025-44", "n": 2 }, { "week": "2026-18", "n": 1 } ], "_tags": [], "_bioc": [ { "branch": "devel", "version": "1.57.0", "bioc": "3.24" }, { "branch": "release", "version": "1.56.0", "bioc": "3.23" } ], "_topics": [ "geneexpression", "genetics", "microarray" ], "_userbio": { "uuid": 2286807, "type": "organization", "name": "Bioconductor", "followers": 468, "description": "Software for the analysis and comprehension of high-throughput genomic data" }, "_downloads": { "count": 577, "source": "https://www.bioconductor.org/packages/stats/bioc/HybridMTest" }, "_mentions": 4, "_searchresults": 12, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/HybridMTest.html", "extra/manual.pdf" ], "_realowner": "bioc", "_cranurl": false, "_exports": [ "grenander.ebp", "hybrid.test", "row.kgrp.shapiro", "row.kruskal.wallis", "row.oneway.anova", "row.pearson", "row.slr.shapiro", "row.spearman" ], "_datasets": [ { "name": "correlation.data", "title": "Sample ExpressionSet object of correlation.data", "object": "correlation.data", "file": "correlation.data.rda", "class": [ "ExpressionSet" ], "fields": [], "table": false, "tojson": false }, { "name": "GroupComp.data", "title": "Sample ExpressionSet of GroupComp.data", "object": "GroupComp.data", "file": "GroupComp.data.rda", "class": [ "ExpressionSet" ], "fields": [], "table": false, "tojson": false } ], "_help": [ { "page": "HybridMTest-package", "title": "A powerful tool in gene expression hypothesis testing.", "topics": [ "HybridMTest-package" ] }, { "page": "correlation.data", "title": "Sample ExpressionSet object of correlation.data", "topics": [ "correlation.data" ] }, { "page": "grenander.ebp", "title": "Grenander EBP.", "topics": [ "grenander.ebp" ] }, { "page": "GroupComp.data", "title": "Sample ExpressionSet of GroupComp.data", "topics": [ "GroupComp.data" ] }, { "page": "hybrid.test", "title": "Hybrid Multiple Testing of Gene Expression Data", "topics": [ "hybrid.test" ] }, { "page": "row.kgrp.shapiro", "title": "Shapiro Wilk test of normality.", "topics": [ "row.kgrp.shapiro" ] }, { "page": "row.kruskal.wallis", "title": "Apply the Kruskal-Wallis test many times", "topics": [ "row.kruskal.wallis" ] }, { "page": "row.oneway.anova", "title": "Perform one-way ANOVA for many variables.", "topics": [ "row.oneway.anova" ] }, { "page": "row.pearson", "title": "Compute the Pearson correlation of a variable x with many variables in a matrix Y", "topics": [ "row.pearson" ] }, { "page": "row.slr.shapiro", "title": "Test normality of residuals for many variables.", "topics": [ "row.slr.shapiro" ] }, { "page": "row.spearman", "title": "Compute Spearmans rank-based correlation of many variables with a variable x", "topics": [ "row.spearman" ] } ], "_rundeps": [ "Biobase", "BiocGenerics", "fdrtool", "generics", "lattice", "MASS", "Matrix", "survival" ], "_vignettes": [ { "source": "HybridMTest.Rnw", "filename": "HybridMTest.pdf", "title": "Hybrid Multiple Testing", "engine": "utils::Sweave", "headings": [ "Introduction", "Data Requirements", "Microarray Data Analysis", "Reference" ], "created": "2013-11-01 20:24:14", "modified": "2013-11-01 20:24:14", "commits": 1 } ], "_score": 3.982271233039569, "_indexed": false, "_nocasepkg": "hybridmtest", "_universes": [ "bioc-release" ], "_indexurl": "https://bioc.r-universe.dev/HybridMTest", "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "1.56.0", "date": "2026-09-18T07:03:44.000Z", "distro": "resolute", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/d61a805c0df92ef10170509ebd79e617f5ab7f3bf72bbc52c79081118f062baa", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.6.1", "os": "linux", "version": "1.56.0", "date": "2026-09-18T07:03:02.000Z", "distro": "resolute", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/166e67dfc0f9b1d59d61d5b48c18a0f8eda77cf81594ccd55be5d95bcb15629b", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.5.3", "os": "mac", "version": "1.56.0", "date": "2026-09-18T07:42:26.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/2ad160a8b1fa724aae9ebda35cc24901b2e85bdd403e8abcdc0c561d69e5473a", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.6.1", "os": "mac", "version": "1.56.0", "date": "2026-09-18T07:43:01.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/9d4fbe58210d6fa1570b4c9a5773cc0e500c147df39dfa4d07484f5cd1e528b6", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.6.0", "os": "wasm", "version": "1.56.0", "date": "2026-09-18T07:02:39.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/517038072a8806d94e3b48f66fc641f2fa1a2c3b5a14f155b73e18aa7ef9014f", "status": "success", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.7.0", "os": "win", "version": "1.56.0", "date": "2026-09-18T07:01:31.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/d5f183592463041d3d4d8fa62b8cd946a41898c7304b017023ed85e51df07bf7", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.5.3", "os": "win", "version": "1.56.0", "date": "2026-09-18T07:01:38.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/e0b87a6126936c28e6b39b21fc1c239b77c97a23b5545ed90df755f762fcbc22", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" }, { "r": "4.6.1", "os": "win", "version": "1.56.0", "date": "2026-09-18T07:01:39.000Z", "commit": "ddc5f7f1b029c5929f0c12686d75c3d09e51f66c", "fileid": "https://r2.ropensci.org/b156e79bf479f2b2328e92c6f5b1450166012f082e473f9d60d5e18940d066ea", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/35317159578" } ] }