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  "Description": "Epigenome-wide association studies (EWAS) detects a large\nnumber of DNA methylation differences, often hundreds of\ndifferentially methylated regions and thousands of CpGs, that\nare significantly associated with a disease, many are located\nin non-coding regions. Therefore, there is a critical need to\nbetter understand the functional impact of these CpG\nmethylations and to further prioritize the significant changes.\nMethReg is an R package for integrative modeling of DNA\nmethylation, target gene expression and transcription factor\nbinding sites data, to systematically identify and rank\nfunctional CpG methylations. MethReg evaluates, prioritizes and\nannotates CpG sites with high regulatory potential using\nmatched methylation and gene expression data, along with\nexternal TF-target interaction databases based on manually\ncuration, ChIP-seq experiments or gene regulatory network\nanalysis.",
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