{
  "_id": "6a1952feacfb0bcc41de02ea",
  "Package": "PhosR",
  "Type": "Package",
  "Title": "A set of methods and tools for comprehensive analysis of\nphosphoproteomics data",
  "Version": "1.22.0",
  "Authors@R": "c(\nperson(\"Pengyi\", \"Yang\", email = \"pengyi.yang@sydney.edu.au\", role = c(\"aut\")),\nperson(\"Di\", \"Xiao\", email = \"di.xiao@sydney.edu.au\", role = c(\"aut\", \"cre\")),\nperson(\"Hani Jieun\", \"Kim\", email = \"jieun.kim@sydney.edu.au\", role = c(\"aut\")))",
  "Description": "PhosR is a package for the comprenhensive analysis of\nphosphoproteomic data. There are two major components to PhosR:\nprocessing and downstream analysis. PhosR consists of various\nprocessing tools for phosphoproteomics data including\nfiltering, imputation, normalisation, and functional analysis\nfor inferring active kinases and signalling pathways.",
  "License": "GPL-3 + file LICENSE",
  "Encoding": "UTF-8",
  "LazyData": "false",
  "RoxygenNote": "7.2.2",
  "VignetteBuilder": "knitr",
  "biocViews": "Software, ResearchField, Proteomics",
  "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libjpeg-dev\nlibpng-dev libxml2-dev libssl-dev zlib1g-dev",
  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 12:53:47 UTC",
  "RemoteUrl": "https://github.com/bioc/PhosR",
  "RemoteRef": "RELEASE_3_23",
  "RemoteSha": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-29 07:36:53 UTC",
    "User": "root"
  },
  "Author": "Pengyi Yang [aut],\nDi Xiao [aut, cre],\nHani Jieun Kim [aut]",
  "Maintainer": "Di Xiao <di.xiao@sydney.edu.au>",
  "MD5sum": "d2dc6280c745e269a153a1c8a5ae40c3",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "PhosR_1.22.0.tar.gz",
  "_fileid": "95659b3cc3b77f751b61a7fd60196c9c93c857a5a97829177f010ac9686eaf84",
  "_filesize": 9199707,
  "_sha256": "95659b3cc3b77f751b61a7fd60196c9c93c857a5a97829177f010ac9686eaf84",
  "_created": "2026-05-29T07:36:53.000Z",
  "_published": "2026-05-29T08:49:02.488Z",
  "_jobs": [
    {
      "job": 78458456022,
      "time": 296,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7285637899"
    },
    {
      "job": 78458456047,
      "time": 441,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7285679241"
    },
    {
      "job": 78458456071,
      "time": 528,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7285703297"
    },
    {
      "job": 78458456074,
      "time": 415,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7286778289"
    },
    {
      "job": 78458456085,
      "time": 431,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7286782759"
    },
    {
      "job": 78457509289,
      "time": 405,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7285550723"
    },
    {
      "job": 78458456078,
      "time": 254,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7285626215"
    },
    {
      "job": 78458456050,
      "time": 848,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7285795577"
    },
    {
      "job": 78458456069,
      "time": 797,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7285779996"
    },
    {
      "job": 78458456106,
      "time": 784,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7285776117"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 1,
    "note": 14
  },
  "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/PhosR",
  "_commit": {
    "id": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
    "time": 1777380827
  },
  "_maintainer": {
    "name": "Di Xiao",
    "email": "di.xiao@sydney.edu.au",
    "login": "dixiao3447",
    "description": "",
    "uuid": 74349753
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 4.2.0",
      "role": "Depends"
    },
    {
      "package": "ruv",
      "role": "Imports"
    },
    {
      "package": "e1071",
      "role": "Imports"
    },
    {
      "package": "dendextend",
      "role": "Imports"
    },
    {
      "package": "limma",
      "role": "Imports"
    },
    {
      "package": "pcaMethods",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "RColorBrewer",
      "role": "Imports"
    },
    {
      "package": "circlize",
      "role": "Imports"
    },
    {
      "package": "dplyr",
      "role": "Imports"
    },
    {
      "package": "igraph",
      "role": "Imports"
    },
    {
      "package": "pheatmap",
      "role": "Imports"
    },
    {
      "package": "preprocessCore",
      "role": "Imports"
    },
    {
      "package": "tidyr",
      "role": "Imports"
    },
    {
      "package": "rlang",
      "role": "Imports"
    },
    {
      "package": "graphics",
      "role": "Imports"
    },
    {
      "package": "grDevices",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "SummarizedExperiment",
      "role": "Imports"
    },
    {
      "package": "methods",
      "role": "Imports"
    },
    {
      "package": "S4Vectors",
      "role": "Imports"
    },
    {
      "package": "BiocGenerics",
      "role": "Imports"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "GGally",
      "role": "Imports"
    },
    {
      "package": "ggdendro",
      "role": "Imports"
    },
    {
      "package": "ggpubr",
      "role": "Imports"
    },
    {
      "package": "network",
      "role": "Imports"
    },
    {
      "package": "reshape2",
      "role": "Imports"
    },
    {
      "package": "ggtext",
      "role": "Imports"
    },
    {
      "package": "stringi",
      "role": "Imports"
    },
    {
      "package": "testthat",
      "role": "Suggests"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rgl",
      "role": "Suggests"
    },
    {
      "package": "sna",
      "role": "Suggests"
    },
    {
      "package": "ClueR",
      "role": "Suggests"
    },
    {
      "package": "directPA",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    },
    {
      "package": "org.Rn.eg.db",
      "role": "Suggests"
    },
    {
      "package": "org.Mm.eg.db",
      "role": "Suggests"
    },
    {
      "package": "reactome.db",
      "role": "Suggests"
    },
    {
      "package": "annotate",
      "role": "Suggests"
    },
    {
      "package": "BiocStyle",
      "role": "Suggests"
    },
    {
      "package": "stringr",
      "role": "Suggests"
    },
    {
      "package": "calibrate",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-34",
      "n": 2
    },
    {
      "week": "2025-37",
      "n": 2
    },
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 1
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.23.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.22.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "software",
    "researchfield",
    "proteomics"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 460,
    "source": "https://www.bioconductor.org/packages/stats/bioc/PhosR"
  },
  "_searchresults": 96,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/PhosR.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "cbind",
    "createFrequencyMat",
    "frequencyScoring",
    "GeneSymbol",
    "GeneSymbol<-",
    "getSPS",
    "kinaseSubstrateHeatmap",
    "kinaseSubstratePred",
    "kinaseSubstrateProfile",
    "kinaseSubstrateScore",
    "Localisation",
    "Localisation<-",
    "matANOVA",
    "meanAbundance",
    "medianScaling",
    "minmax",
    "mIntersect",
    "mUnion",
    "pathwayOverrepresent",
    "pathwayRankBasedEnrichment",
    "phosCollapse",
    "PhosphoExperiment",
    "plotKinaseNetwork",
    "plotQC",
    "plotSignalomeMap",
    "ptImpute",
    "rbind",
    "Residue",
    "Residue<-",
    "RUVphospho",
    "RUVproteome",
    "scImpute",
    "selectGrps",
    "selectLocalisedSites",
    "selectOverallPercent",
    "selectTimes",
    "Sequence",
    "Sequence<-",
    "Signalomes",
    "Site",
    "Site<-",
    "siteAnnotate",
    "standardise",
    "tImpute",
    "UniprotID",
    "UniprotID<-"
  ],
  "_datasets": [
    {
      "name": "hSEGs",
      "title": "A list of Stably Expressed Genes (SEGs)",
      "object": "SEGs",
      "file": "SEGs.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "KinaseFamily",
      "title": "KinaseFamily",
      "object": "KinaseFamily",
      "file": "KinaseFamily.rda",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "gene_name",
        "gene_symbol",
        "kinase_group",
        "kinase_family",
        "kinase_subfamily",
        "human_ortholog"
      ],
      "rows": 425,
      "table": true,
      "tojson": true
    },
    {
      "name": "motif.human.list",
      "title": "List of human kinase motifs",
      "object": "KinaseMotifs",
      "file": "KinaseMotifs.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "motif.mouse.list",
      "title": "List of mouse kinase motifs",
      "object": "KinaseMotifs",
      "file": "KinaseMotifs.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "motif.rat.list",
      "title": "List of rat kinase motifs",
      "object": "KinaseMotifs",
      "file": "KinaseMotifs.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "mSEGs",
      "title": "A list of Stably Expressed Genes (SEGs)",
      "object": "SEGs",
      "file": "SEGs.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "phospho.cells.Ins",
      "title": "phospho.cells.Ins",
      "object": "phospho.cells.Ins.sample",
      "file": "phospho.cells.Ins.sample.rda",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "Intensity.FL83B_Control_1",
        "Intensity.FL83B_Control_2",
        "Intensity.FL83B_Control_3",
        "Intensity.FL83B_Control_4",
        "Intensity.FL83B_Control_5",
        "Intensity.FL83B_Control_6",
        "Intensity.FL83B_Ins_1",
        "Intensity.FL83B_Ins_2",
        "Intensity.FL83B_Ins_3",
        "Intensity.FL83B_Ins_4",
        "Intensity.FL83B_Ins_5",
        "Intensity.FL83B_Ins_6",
        "Intensity.Hepa1.6_Control_1",
        "Intensity.Hepa1.6_Control_2",
        "Intensity.Hepa1.6_Control_3",
        "Intensity.Hepa1.6_Control_4",
        "Intensity.Hepa1.6_Control_5",
        "Intensity.Hepa1.6_Control_6",
        "Intensity.Hepa1.6_Ins_1",
        "Intensity.Hepa1.6_Ins_2",
        "Intensity.Hepa1.6_Ins_3",
        "Intensity.Hepa1.6_Ins_4",
        "Intensity.Hepa1.6_Ins_5",
        "Intensity.Hepa1.6_Ins_6"
      ],
      "rows": 5000,
      "table": true,
      "tojson": true
    },
    {
      "name": "phospho.cells.Ins.pe",
      "title": "phospho.cells.Ins",
      "object": "phospho.cells.Ins.pe",
      "file": "phospho.cells.Ins.pe.rda",
      "class": [
        "PhosphoExperiment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "phospho.L6.ratio",
      "title": "phospho.L6.ratio",
      "object": "phospho_L6_ratio",
      "file": "phospho_L6_ratio.RData",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "AICAR_exp1",
        "AICAR_exp2",
        "AICAR_exp3",
        "AICAR_exp4",
        "Ins_exp1",
        "Ins_exp2",
        "Ins_exp3",
        "Ins_exp4",
        "AICARIns_exp1",
        "AICARIns_exp2",
        "AICARIns_exp3",
        "AICARIns_exp4"
      ],
      "rows": 6660,
      "table": true,
      "tojson": true
    },
    {
      "name": "phospho.L6.ratio.pe",
      "title": "phospho_L6_ratio_pe",
      "object": "phospho_L6_ratio_pe",
      "file": "phospho_L6_ratio_pe.rda",
      "class": [
        "PhosphoExperiment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "phospho.liver.Ins.TC.ratio.RUV",
      "title": "phospho_liverInsTC_RUV_sample",
      "object": "phospho_liverInsTC_RUV_sample",
      "file": "phospho_liverInsTC_RUV_sample.rda",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "Intensity.Liver_Ins_0s_Bio7",
        "Intensity.Liver_Ins_0s_Bio8",
        "Intensity.Liver_Ins_0s_Bio9",
        "Intensity.Liver_Ins_0s_Bio10",
        "Intensity.Liver_Ins_0s_Bio11",
        "Intensity.Liver_Ins_0s_Bio12",
        "Intensity.Liver_Ins_0s_Bio13",
        "Intensity.Liver_Ins_0s_Bio14",
        "Intensity.Liver_Ins_0s_Bio1",
        "Intensity.Liver_Ins_0s_Bio2",
        "Intensity.Liver_Ins_0s_Bio3",
        "Intensity.Liver_Ins_0s_Bio4",
        "Intensity.Liver_Ins_0s_Bio5",
        "Intensity.Liver_Ins_0s_Bio6",
        "Intensity.Liver_Ins_5s_Bio7",
        "Intensity.Liver_Ins_5s_Bio8",
        "Intensity.Liver_Ins_5s_Bio9",
        "Intensity.Liver_Ins_5s_Bio10",
        "Intensity.Liver_Ins_5s_Bio11",
        "Intensity.Liver_Ins_5s_Bio12",
        "Intensity.Liver_Ins_5s_Bio13",
        "Intensity.Liver_Ins_5s_Bio14",
        "Intensity.Liver_Ins_5s_Bio15",
        "Intensity.Liver_Ins_10s_Bio7",
        "Intensity.Liver_Ins_10s_Bio8",
        "Intensity.Liver_Ins_10s_Bio9",
        "Intensity.Liver_Ins_10s_Bio10",
        "Intensity.Liver_Ins_10s_Bio11",
        "Intensity.Liver_Ins_10s_Bio12",
        "Intensity.Liver_Ins_10s_Bio13",
        "Intensity.Liver_Ins_10s_Bio14",
        "Intensity.Liver_Ins_10s_Bio15",
        "Intensity.Liver_Ins_15s_Bio7",
        "Intensity.Liver_Ins_15s_Bio8",
        "Intensity.Liver_Ins_15s_Bio9",
        "Intensity.Liver_Ins_15s_Bio10",
        "Intensity.Liver_Ins_15s_Bio11",
        "Intensity.Liver_Ins_15s_Bio12",
        "Intensity.Liver_Ins_15s_Bio13",
        "Intensity.Liver_Ins_15s_Bio14",
        "Intensity.Liver_Ins_30s_Bio7",
        "Intensity.Liver_Ins_30s_Bio8",
        "Intensity.Liver_Ins_30s_Bio9",
        "Intensity.Liver_Ins_30s_Bio10",
        "Intensity.Liver_Ins_30s_Bio11",
        "Intensity.Liver_Ins_30s_Bio12",
        "Intensity.Liver_Ins_30s_Bio13",
        "Intensity.Liver_Ins_30s_Bio14",
        "Intensity.Liver_Ins_30s_Bio1",
        "Intensity.Liver_Ins_30s_Bio2",
        "Intensity.Liver_Ins_30s_Bio3",
        "Intensity.Liver_Ins_30s_Bio4",
        "Intensity.Liver_Ins_30s_Bio5",
        "Intensity.Liver_Ins_30s_Bio6",
        "Intensity.Liver_Ins_1m_Bio1",
        "Intensity.Liver_Ins_1m_Bio2",
        "Intensity.Liver_Ins_1m_Bio3",
        "Intensity.Liver_Ins_1m_Bio4",
        "Intensity.Liver_Ins_1m_Bio5",
        "Intensity.Liver_Ins_1m_Bio6",
        "Intensity.Liver_Ins_2m_Bio1",
        "Intensity.Liver_Ins_2m_Bio2",
        "Intensity.Liver_Ins_2m_Bio3",
        "Intensity.Liver_Ins_2m_Bio4",
        "Intensity.Liver_Ins_2m_Bio5",
        "Intensity.Liver_Ins_2m_Bio6",
        "Intensity.Liver_Ins_3m_Bio1",
        "Intensity.Liver_Ins_3m_Bio2",
        "Intensity.Liver_Ins_3m_Bio3",
        "Intensity.Liver_Ins_3m_Bio4",
        "Intensity.Liver_Ins_3m_Bio5",
        "Intensity.Liver_Ins_3m_Bio6",
        "Intensity.Liver_Ins_4m_Bio1",
        "Intensity.Liver_Ins_4m_Bio2",
        "Intensity.Liver_Ins_4m_Bio3",
        "Intensity.Liver_Ins_4m_Bio4",
        "Intensity.Liver_Ins_4m_Bio5",
        "Intensity.Liver_Ins_4m_Bio6",
        "Intensity.Liver_Ins_6m_Bio1",
        "Intensity.Liver_Ins_6m_Bio2",
        "Intensity.Liver_Ins_6m_Bio3",
        "Intensity.Liver_Ins_6m_Bio4",
        "Intensity.Liver_Ins_6m_Bio5",
        "Intensity.Liver_Ins_6m_Bio6",
        "Intensity.Liver_Ins_10m_Bio1",
        "Intensity.Liver_Ins_10m_Bio2",
        "Intensity.Liver_Ins_10m_Bio3",
        "Intensity.Liver_Ins_10m_Bio4",
        "Intensity.Liver_Ins_10m_Bio5",
        "Intensity.Liver_Ins_10m_Bio6"
      ],
      "rows": 800,
      "table": true,
      "tojson": true
    },
    {
      "name": "phospho.liver.Ins.TC.ratio.RUV.pe",
      "title": "phospho.liver.Ins.TC.ratio.RUV.pe",
      "object": "phospho.liver.Ins.TC.ratio.RUV.pe",
      "file": "phospho.liver.Ins.TC.ratio.RUV.pe.RData",
      "class": [
        "PhosphoExperiment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "PhosphoSite.human",
      "title": "PhosphoSitePlus annotations for human",
      "object": "PhosphoSitePlus",
      "file": "PhosphoSitePlus.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "PhosphoSite.mouse",
      "title": "PhosphoSitePlus annotations for mouse",
      "object": "PhosphoSitePlus",
      "file": "PhosphoSitePlus.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "PhosphoSite.rat",
      "title": "PhosphoSitePlus annotations for rat",
      "object": "PhosphoSitePlus",
      "file": "PhosphoSitePlus.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "SPSs",
      "title": "A list of Stably Phosphorylated Sites (SPSs)",
      "object": "SPSs",
      "file": "SPSs.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "createFrequencyMat",
      "title": "Create frequency matrix",
      "topics": [
        "createFrequencyMat"
      ]
    },
    {
      "page": "frequencyScoring",
      "title": "Frequency scoring",
      "topics": [
        "frequencyScoring"
      ]
    },
    {
      "page": "getSPS",
      "title": "Generate set of stable phosphoporylated sites",
      "topics": [
        "getSPS"
      ]
    },
    {
      "page": "hSEGs",
      "title": "A list of Stably Expressed Genes (SEGs)",
      "topics": [
        "hSEGs"
      ]
    },
    {
      "page": "KinaseFamily",
      "title": "KinaseFamily",
      "topics": [
        "KinaseFamily"
      ]
    },
    {
      "page": "kinaseSubstrateHeatmap",
      "title": "Kinase-substrate annotation prioritisation heatmap",
      "topics": [
        "kinaseSubstrateHeatmap"
      ]
    },
    {
      "page": "kinaseSubstratePred",
      "title": "kinaseSubstratePred",
      "topics": [
        "kinaseSubstratePred"
      ]
    },
    {
      "page": "kinaseSubstrateProfile",
      "title": "Kinase substrate profiling",
      "topics": [
        "kinaseSubstrateProfile"
      ]
    },
    {
      "page": "kinaseSubstrateScore",
      "title": "Kinase substrate scoring",
      "topics": [
        "kinaseSubstrateScore"
      ]
    },
    {
      "page": "matANOVA",
      "title": "ANOVA test",
      "topics": [
        "matANOVA"
      ]
    },
    {
      "page": "meanAbundance",
      "title": "Obtain average expression from replicates",
      "topics": [
        "meanAbundance"
      ]
    },
    {
      "page": "medianScaling",
      "title": "Median centering and scaling",
      "topics": [
        "medianScaling"
      ]
    },
    {
      "page": "minmax",
      "title": "Minmax scaling",
      "topics": [
        "minmax"
      ]
    },
    {
      "page": "mIntersect",
      "title": "Multi-intersection, union",
      "topics": [
        "mIntersect",
        "mUnion"
      ]
    },
    {
      "page": "motif.human.list",
      "title": "List of human kinase motifs",
      "topics": [
        "motif.human.list"
      ]
    },
    {
      "page": "motif.mouse.list",
      "title": "List of mouse kinase motifs",
      "topics": [
        "motif.mouse.list"
      ]
    },
    {
      "page": "motif.rat.list",
      "title": "List of rat kinase motifs",
      "topics": [
        "motif.rat.list"
      ]
    },
    {
      "page": "mSEGs",
      "title": "A list of Stably Expressed Genes (SEGs)",
      "topics": [
        "mSEGs"
      ]
    },
    {
      "page": "pathwayOverrepresent",
      "title": "phosphosite/Gene set over-representation analysis",
      "topics": [
        "pathwayOverrepresent"
      ]
    },
    {
      "page": "pathwayRankBasedEnrichment",
      "title": "Phosphosite/Gene set enrichment analysis",
      "topics": [
        "pathwayRankBasedEnrichment"
      ]
    },
    {
      "page": "phosCollapse",
      "title": "Summarising phosphosites to proteins",
      "topics": [
        "phosCollapse"
      ]
    },
    {
      "page": "phospho.cells.Ins",
      "title": "phospho.cells.Ins",
      "topics": [
        "phospho.cells.Ins",
        "phospho.cells.Ins.pe"
      ]
    },
    {
      "page": "phospho.L6.ratio",
      "title": "phospho.L6.ratio",
      "topics": [
        "phospho.L6.ratio"
      ]
    },
    {
      "page": "phospho.L6.ratio.pe",
      "title": "phospho_L6_ratio_pe",
      "topics": [
        "phospho.L6.ratio.pe"
      ]
    },
    {
      "page": "phospho.liver.Ins.TC.ratio.RUV",
      "title": "phospho_liverInsTC_RUV_sample",
      "topics": [
        "phospho.liver.Ins.TC.ratio.RUV"
      ]
    },
    {
      "page": "phospho.liver.Ins.TC.ratio.RUV.pe",
      "title": "phospho.liver.Ins.TC.ratio.RUV.pe",
      "topics": [
        "phospho.liver.Ins.TC.ratio.RUV.pe"
      ]
    },
    {
      "page": "PhosphoExperiment",
      "title": "The PhosphoExperiment class",
      "topics": [
        "coerce,",
        "PhosphoExperiment",
        "PhosphoExperiment-class",
        "PhosphoExperiment-method",
        "SummarizedExperiment,"
      ]
    },
    {
      "page": "PhosphoSite.human",
      "title": "PhosphoSitePlus annotations for human",
      "topics": [
        "PhosphoSite.human"
      ]
    },
    {
      "page": "PhosphoSite.mouse",
      "title": "PhosphoSitePlus annotations for mouse",
      "topics": [
        "PhosphoSite.mouse"
      ]
    },
    {
      "page": "PhosphoSite.rat",
      "title": "PhosphoSitePlus annotations for rat",
      "topics": [
        "PhosphoSite.rat"
      ]
    },
    {
      "page": "plotKinaseNetwork",
      "title": "Plot kinase network",
      "topics": [
        "plotKinaseNetwork"
      ]
    },
    {
      "page": "plotQC",
      "title": "A set of function for data QC plot",
      "topics": [
        "plotQC"
      ]
    },
    {
      "page": "plotSignalomeMap",
      "title": "Plot signalome map",
      "topics": [
        "plotSignalomeMap"
      ]
    },
    {
      "page": "PhosphoExperiment-methods",
      "title": "PhosphoExperiment object accessors",
      "topics": [
        "GeneSymbol",
        "GeneSymbol,PhosphoExperiment-method",
        "GeneSymbol<-",
        "GeneSymbol<-,PhosphoExperiment-method",
        "Localisation",
        "Localisation,PhosphoExperiment-method",
        "Localisation<-",
        "Localisation<-,PhosphoExperiment-method",
        "PPE-accessors",
        "Residue",
        "Residue,PhosphoExperiment-method",
        "Residue<-",
        "Residue<-,PhosphoExperiment-method",
        "Sequence",
        "Sequence,PhosphoExperiment-method",
        "Sequence<-",
        "Sequence<-,PhosphoExperiment-method",
        "Site",
        "Site,PhosphoExperiment-method",
        "Site<-",
        "Site<-,PhosphoExperiment-method",
        "UniprotID",
        "UniprotID,PhosphoExperiment-method",
        "UniprotID<-",
        "UniprotID<-,PhosphoExperiment-method"
      ]
    },
    {
      "page": "PhosphoExperiment-operate",
      "title": "PhosphoExperiment object subset, combine methods",
      "topics": [
        "cbind",
        "cbind,PhosphoExperiment-method",
        "PPE-operate",
        "rbind",
        "rbind,PhosphoExperiment-method",
        "[",
        "[,PhosphoExperiment,ANY,ANY,ANY-method",
        "[<-",
        "[<-,PhosphoExperiment,ANY,ANY,ANY-method"
      ]
    },
    {
      "page": "ptImpute",
      "title": "Paired-tail (pt) based impute",
      "topics": [
        "ptImpute"
      ]
    },
    {
      "page": "RUVphospho",
      "title": "RUV for phosphoproteomics data normalisation",
      "topics": [
        "RUVphospho",
        "RUVproteome"
      ]
    },
    {
      "page": "scImpute",
      "title": "Site- and condition-specific (sc) impute",
      "topics": [
        "scImpute"
      ]
    },
    {
      "page": "selectGrps",
      "title": "Select by treatment groups (replicate block)",
      "topics": [
        "selectGrps"
      ]
    },
    {
      "page": "selectLocalisedSites",
      "title": "Select phosphosites by localisation score",
      "topics": [
        "selectLocalisedSites"
      ]
    },
    {
      "page": "selectOverallPercent",
      "title": "Select phosphosite by percentage of quantification",
      "topics": [
        "selectOverallPercent"
      ]
    },
    {
      "page": "selectTimes",
      "title": "selectTimes",
      "topics": [
        "selectTimes"
      ]
    },
    {
      "page": "Signalomes",
      "title": "PhosR Signalomes",
      "topics": [
        "Signalomes"
      ]
    },
    {
      "page": "siteAnnotate",
      "title": "Phosphosite annotation",
      "topics": [
        "siteAnnotate"
      ]
    },
    {
      "page": "SPSs",
      "title": "A list of Stably Phosphorylated Sites (SPSs)",
      "topics": [
        "SPSs"
      ]
    },
    {
      "page": "standardise",
      "title": "Standardisation",
      "topics": [
        "standardise"
      ]
    },
    {
      "page": "tImpute",
      "title": "Tail-based impute",
      "topics": [
        "tImpute"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/PhosR/raw/RELEASE_3_23/README.md",
  "_rundeps": [
    "abind",
    "backports",
    "Biobase",
    "BiocGenerics",
    "boot",
    "broom",
    "car",
    "carData",
    "circlize",
    "class",
    "cli",
    "coda",
    "colorspace",
    "commonmark",
    "corrplot",
    "cowplot",
    "cpp11",
    "crayon",
    "curl",
    "DelayedArray",
    "dendextend",
    "Deriv",
    "doBy",
    "dplyr",
    "e1071",
    "farver",
    "forcats",
    "forecast",
    "Formula",
    "fracdiff",
    "generics",
    "GenomicRanges",
    "GGally",
    "ggdendro",
    "ggplot2",
    "ggpubr",
    "ggrepel",
    "ggsci",
    "ggsignif",
    "ggstats",
    "ggtext",
    "GlobalOptions",
    "glue",
    "gridExtra",
    "gridtext",
    "gtable",
    "hms",
    "igraph",
    "IRanges",
    "isoband",
    "jpeg",
    "labeling",
    "lattice",
    "lifecycle",
    "limma",
    "litedown",
    "lme4",
    "lmtest",
    "magrittr",
    "markdown",
    "MASS",
    "Matrix",
    "MatrixGenerics",
    "MatrixModels",
    "matrixStats",
    "mgcv",
    "microbenchmark",
    "minqa",
    "modelr",
    "network",
    "nlme",
    "nloptr",
    "nnet",
    "numDeriv",
    "patchwork",
    "pbkrtest",
    "pcaMethods",
    "pheatmap",
    "pillar",
    "pkgconfig",
    "plyr",
    "png",
    "polynom",
    "preprocessCore",
    "prettyunits",
    "progress",
    "proxy",
    "purrr",
    "quantreg",
    "R6",
    "rbibutils",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "Rdpack",
    "reformulas",
    "reshape2",
    "rlang",
    "rstatix",
    "ruv",
    "S4Arrays",
    "S4Vectors",
    "S7",
    "scales",
    "Seqinfo",
    "shape",
    "SparseArray",
    "SparseM",
    "statmod",
    "statnet.common",
    "stringi",
    "stringr",
    "SummarizedExperiment",
    "survival",
    "tibble",
    "tidyr",
    "tidyselect",
    "timeDate",
    "urca",
    "utf8",
    "vctrs",
    "viridis",
    "viridisLite",
    "withr",
    "xfun",
    "xml2",
    "XVector",
    "zoo"
  ],
  "_vignettes": [
    {
      "source": "PhosR.Rmd",
      "filename": "PhosR.html",
      "title": "An introduction to PhosR package",
      "author": "Taiyun Kim, Hani Jieun Kim, Di Xiao, Pengyi Yang",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Installation",
        "Loading packages and data",
        "Setting up the PhosphoExperiment object",
        "Part A. Preprocessing",
        "Imputation",
        "Setting up the data",
        "Filtering of phosphosites",
        "Imputation of phosphosites",
        "Site- and condition-specific imputation",
        "Paired tail-based imputation",
        "Quantification plots",
        "Batch correction",
        "Diagnosing batch effect",
        "Correcting batch effect",
        "Quality control",
        "Generating SPSs",
        "Part B. Downstream analysis",
        "Pathway analysis",
        "1-dimensional enrichment analysis",
        "Prepare the Reactome annotation",
        "Perform 1D gene-centric pathway analysis",
        "2- and 3-dimensional signalling pathway analysis",
        "Site- and gene- centric analysis",
        "Gene-centric analyses of the liver phosphoproteome data",
        "Site-centric analyses of the liver phosphoproteome data",
        "Signalomes",
        "Generation of kinase-substrate relationship scores",
        "Signalome construction",
        "Generate signalome map",
        "Generate signalome network",
        "Session Info"
      ],
      "created": "2020-06-30 00:48:25",
      "modified": "2021-04-23 12:47:59",
      "commits": 19
    }
  ],
  "_score": 5.28330122870355,
  "_indexed": false,
  "_nocasepkg": "phosr",
  "_universes": [
    "bioc-release"
  ],
  "_indexurl": "https://bioc.r-universe.dev/PhosR",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.22.0",
      "date": "2026-05-29T07:41:23.000Z",
      "distro": "noble",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "41d1ba61aaa676246abcd1a23f9db6a5c1cb4ca99a83dcbc6f4285b69c31c223",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.22.0",
      "date": "2026-05-29T07:42:02.000Z",
      "distro": "noble",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "79c416040131437c1a967b3033e1e8180a1e778d675490273726f5a2c1737f26",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.22.0",
      "date": "2026-05-29T08:45:11.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "e647327f1d2d6debbd043e1964eda9984c0f32a5584e859dd7f0e25573b90131",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.22.0",
      "date": "2026-05-29T08:45:45.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "55b7d5bdfe98b8c425d5f909058a66b9fd0650a27c763946973ffd3d7c390e86",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.22.0",
      "date": "2026-05-29T07:41:38.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "1efe7af98f38a36a7dcd1d8c16a37ccbc262f02410535f70d241e633f148675f",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.22.0",
      "date": "2026-05-29T07:46:34.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "dc28147eb6aabd302a77dcbfe686cdcb25623028311c1c1b0fb353fe3ff597c5",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.22.0",
      "date": "2026-05-29T07:45:48.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "d5ddfc3097ae2b0b5733f704bbab49370d3b767cf390a81684391c3fafcfcc34",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.22.0",
      "date": "2026-05-29T07:45:47.000Z",
      "commit": "5abc7acea28880d1d603bd55ad7e00fad5e9ef25",
      "fileid": "69c0a02b0cf286777df1c0bba7328e8a4de9abe487538e11fb0c8eeab6f80d5a",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26624372270"
    }
  ]
}