{
  "_id": "6a13f2e0acfb0bcc41d31dda",
  "Package": "RNAsense",
  "Type": "Package",
  "Title": "Analysis of Time-Resolved RNA-Seq Data",
  "Version": "1.26.0",
  "Authors@R": "c(person(\"Marcus\", \"Rosenblatt\", email = \"marcus.rosenblatt@gmail.com\", role = \"cre\"),\nperson(\"Gao\", \"Meijang\", role = \"aut\"),\nperson(\"Helge\", \"Hass\", role = \"aut\"),\nperson(\"Daria\", \"Onichtchouk\", role = \"aut\"))",
  "Description": "RNA-sense tool compares RNA-seq time curves in two\nexperimental conditions, i.e. wild-type and mutant, and works\nin three steps. At Step 1, it builds expression profile for\neach transcript in one condition (i.e. wild-type) and tests if\nthe transcript abundance grows or decays significantly. Dynamic\ntranscripts are then sorted to non-overlapping groups (time\nprofiles) by the time point of switch up or down. At Step 2,\nRNA-sense outputs the groups of differentially expressed\ntranscripts, which are up- or downregulated in the mutant\ncompared to the wild-type at each time point. At Step 3,\nCorrelations (Fisher's exact test) between the outputs of Step\n1 (switch up- and switch down- time profile groups) and the\noutputs of Step2 (differentially expressed transcript groups)\nare calculated. The results of the correlation analysis are\nprinted as two-dimensional color plot, with time profiles and\ndifferential expression groups at y- and x-axis, respectively,\nand facilitates the biological interpretation of the data.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "LazyData": "false",
  "RoxygenNote": "6.1.1",
  "BugReports": "https://github.com/marcusrosenblatt/RNAsense",
  "biocViews": "RNASeq, GeneExpression, DifferentialExpression",
  "VignetteBuilder": "knitr",
  "Config/pak/sysreqs": "libicu-dev zlib1g-dev",
  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 12:51:23 UTC",
  "RemoteUrl": "https://github.com/bioc/RNAsense",
  "RemoteRef": "RELEASE_3_23",
  "RemoteSha": "c8168cea7002ffa2d180b920c92821ae334d1fca",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-25 06:43:45 UTC",
    "User": "root"
  },
  "Author": "Marcus Rosenblatt [cre],\nGao Meijang [aut],\nHelge Hass [aut],\nDaria Onichtchouk [aut]",
  "Maintainer": "Marcus Rosenblatt <marcus.rosenblatt@gmail.com>",
  "MD5sum": "438d7d15dfe863e53012ffdde0e761f9",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "RNAsense_1.26.0.tar.gz",
  "_fileid": "25d2300cce5d3cc997c5c953d83c0806ecf11b8842dc57a90475f50e53842bd3",
  "_filesize": 1105779,
  "_sha256": "25d2300cce5d3cc997c5c953d83c0806ecf11b8842dc57a90475f50e53842bd3",
  "_created": "2026-05-25T06:43:45.000Z",
  "_published": "2026-05-25T06:57:36.028Z",
  "_jobs": [
    {
      "job": 77668641286,
      "time": 136,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7193097486"
    },
    {
      "job": 77668641292,
      "time": 687,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7193217082"
    },
    {
      "job": 77668641308,
      "time": 780,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7193237840"
    },
    {
      "job": 77668641280,
      "time": 360,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7193145396"
    },
    {
      "job": 77668641274,
      "time": 393,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7193152986"
    },
    {
      "job": 77667877592,
      "time": 413,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7193066816"
    },
    {
      "job": 77668641285,
      "time": 125,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7193095038"
    },
    {
      "job": 77668641304,
      "time": 744,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7193229325"
    },
    {
      "job": 77668641302,
      "time": 749,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7193230696"
    },
    {
      "job": 77668641282,
      "time": 721,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7193224420"
    }
  ],
  "_bioccheck": {
    "error": 0,
    "warning": 0,
    "note": 9
  },
  "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/RNAsense",
  "_commit": {
    "id": "c8168cea7002ffa2d180b920c92821ae334d1fca",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
    "time": 1777380683
  },
  "_maintainer": {
    "name": "Marcus Rosenblatt",
    "email": "marcus.rosenblatt@gmail.com",
    "login": "marcusrosenblatt",
    "description": "I am interested in music, chess, volleyball and systems biology...",
    "uuid": 14975596
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.6",
      "role": "Depends"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "parallel",
      "role": "Imports"
    },
    {
      "package": "NBPSeq",
      "role": "Imports"
    },
    {
      "package": "qvalue",
      "role": "Imports"
    },
    {
      "package": "SummarizedExperiment",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    },
    {
      "package": "utils",
      "role": "Imports"
    },
    {
      "package": "methods",
      "role": "Imports"
    },
    {
      "package": "knitr",
      "role": "Suggests"
    },
    {
      "package": "rmarkdown",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 1
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.27.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.26.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "rnaseq",
    "geneexpression",
    "differentialexpression"
  ],
  "_stars": 1,
  "_contributors": [
    {
      "user": "marcusrosenblatt",
      "count": 57,
      "uuid": 14975596
    }
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 336,
    "source": "https://www.bioconductor.org/packages/stats/bioc/RNAsense"
  },
  "_devurl": "https://github.com/marcusrosenblatt/rnasense",
  "_searchresults": 2,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/RNAsense.html",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/marcusrosenblatt/rnasense",
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "combineResults",
    "getFC",
    "getSwitch",
    "outputGeneTables",
    "plotSSGS"
  ],
  "_datasets": [
    {
      "name": "MZsox",
      "title": "Time resolved RNA seq data for early zygotic development of zebra fish.",
      "object": "MZsox",
      "file": "MZsox.RData",
      "class": [
        "SummarizedExperiment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "combineResults",
      "title": "Combine results",
      "topics": [
        "combineResults"
      ]
    },
    {
      "page": "getFC",
      "title": "Detect fold changes",
      "topics": [
        "getFC"
      ]
    },
    {
      "page": "getSwitch",
      "title": "Detect switching genes",
      "topics": [
        "getSwitch"
      ]
    },
    {
      "page": "MZsox",
      "title": "Time resolved RNA seq data for early zygotic development of zebra fish.",
      "topics": [
        "MZsox"
      ]
    },
    {
      "page": "outputGeneTables",
      "title": "Output gene tables",
      "topics": [
        "outputGeneTables"
      ]
    },
    {
      "page": "plotSSGS",
      "title": "plot SSGS gene classes",
      "topics": [
        "plotSSGS"
      ]
    }
  ],
  "_rundeps": [
    "abind",
    "Biobase",
    "BiocGenerics",
    "cli",
    "cpp11",
    "DelayedArray",
    "farver",
    "generics",
    "GenomicRanges",
    "ggplot2",
    "glue",
    "gtable",
    "IRanges",
    "isoband",
    "labeling",
    "lattice",
    "lifecycle",
    "magrittr",
    "Matrix",
    "MatrixGenerics",
    "matrixStats",
    "NBPSeq",
    "plyr",
    "qvalue",
    "R6",
    "RColorBrewer",
    "Rcpp",
    "reshape2",
    "rlang",
    "S4Arrays",
    "S4Vectors",
    "S7",
    "scales",
    "Seqinfo",
    "SparseArray",
    "stringi",
    "stringr",
    "SummarizedExperiment",
    "vctrs",
    "viridisLite",
    "withr",
    "XVector"
  ],
  "_vignettes": [
    {
      "source": "example.Rmd",
      "filename": "example.html",
      "title": "RNAsense",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduction",
        "Installation",
        "Step-by-step Tutorial",
        "Session Info"
      ],
      "created": "2019-08-03 11:00:29",
      "modified": "2019-10-22 12:19:52",
      "commits": 14
    }
  ],
  "_score": 3.3010299956639813,
  "_indexed": false,
  "_nocasepkg": "rnasense",
  "_universes": [
    "bioc-release"
  ],
  "_indexurl": "https://bioc.r-universe.dev/RNAsense",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.26.0",
      "date": "2026-05-25T06:47:26.000Z",
      "distro": "noble",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "08b360fd311b35a56cacbbb5a685e185f8e906fe0d5e75c60c7b5d902f1fac09",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.26.0",
      "date": "2026-05-25T06:47:16.000Z",
      "distro": "noble",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "384a648b4f14ff2e2d759a984fee23ef04db9e2a1088de42deac2d452c5356f7",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.26.0",
      "date": "2026-05-25T06:45:23.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "78b133d8d3a9111c400d273fb4a420f700af5d184a25ae05b3ef483dcf2dfb91",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.26.0",
      "date": "2026-05-25T06:45:19.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "fb874857139fd4acf80df2f6a0c687707157312892f3d9a693c5b602e92ab562",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.26.0",
      "date": "2026-05-25T06:46:17.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "86f0a7e3f89a0dc5f2fea12fe8018ad51f7aabb682e65b65582bc9a133dd756e",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.26.0",
      "date": "2026-05-25T06:45:21.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "7cb4eb863f5183c5920dee7657c57a698133e6054560b4184408d6322cd28b8a",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.26.0",
      "date": "2026-05-25T06:45:09.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "685bc8a9493aff7b8f78d26ef78fb265339a715f8e77ab52b1b377802fc485ca",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.26.0",
      "date": "2026-05-25T06:45:14.000Z",
      "commit": "c8168cea7002ffa2d180b920c92821ae334d1fca",
      "fileid": "73d94cb6bbabdc76c675a17fd60be085f9d832c20af52c65482933590b1b492f",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26387063684"
    }
  ]
}