{ "_id": "6a1b0ba11d7bb097a0a07198", "Package": "RadioGx", "Type": "Package", "Title": "Analysis of Large-Scale Radio-Genomic Data", "Version": "2.16.0", "Date": "2023-04-19", "Authors@R": "c(\nperson(\"Venkata\",\"Manem\", email = \"mail2mvskumar@gmail.com\",\nrole = c(\"aut\")),\nperson(\"Petr\",\"Smirnov\", email = \"petr.smirnov@uhnresearch.ca\",\nrole = c(\"aut\")),\nperson(\"Ian\",\"Smith\", email = \"ianc.smith@mail.utoronto.ca\",\nrole = c(\"aut\")),\nperson(\"Meghan\",\"Lambie\", email = \"megan.lambie@mail.utoronto.ca\",\nrole = c(\"aut\")),\nperson(\"Christopher\",\"Eeles\", email = \"christopher.eeles@uhnresearch.ca\",\nrole = c(\"aut\")),\nperson(\"Scott\", \"Bratman\", email = \"scott.bratman@rmp.uhn.ca\",\nrole = c(\"aut\")),\nperson(\"Jermiah\", \"Joseph\", email = \"jermiah.joseph@uhn.ca\",\nrole = c(\"aut\")),\nperson(\"Benjamin\",\"Haibe-Kains\", email = \"benjamin.haibe.kains@utoronto.ca\",\nrole = c(\"aut\",\"cre\"))\n)", "Description": "Computational tool box for radio-genomic analysis which\nintegrates radio-response data, radio-biological modelling and\ncomprehensive cell line annotations for hundreds of cancer cell\nlines. The 'RadioSet' class enables creation and manipulation\nof standardized datasets including information about cancer\ncells lines, radio-response assays and dose-response\nindicators. Included methods allow fitting and plotting\ndose-response data using established radio-biological models\nalong with quality control to validate results. Additional\nfunctions related to fitting and plotting dose response curves,\nquantifying statistical correlation and calculating area under\nthe curve (AUC) or survival fraction (SF) are included. For\nmore details please see the included documentation, references,\nas well as: Manem, V. et al (2018) .", "License": "GPL-3", "VignetteBuilder": "knitr", "VignetteEngine": "knitr::rmarkdown", "Encoding": "UTF-8", "LazyData": "true", "biocViews": "Software, Pharmacogenetics, QualityControl, Survival,\nPharmacogenomics, Classification", "RoxygenNote": "7.2.3", "Collate": "'OERmodel.R' 'RadioSet-class.R' 'RadioSet-accessors.R'\n'computeAUC.R' 'computeD10.R' 'computeSF2.R'\n'computeSensitivity.R' 'datasets.R' 'doseResponseCurve.R'\n'downloadRSet.R' 'geneDrugSensitivity.R' 'linearQuadratic.R'\n'linearQuadraticInv.R' 'linearQuadraticModel.R'\n'makeGrittyGuess.R' 'plotCurve.R' 'radSensitivitySig.R'\n'rankGeneRadSensitivity.R' 'signatureClass.R'\n'subsetTo-methods.R' 'summarizeMolecularProfiles-methods.R'\n'summarizeSensitivityProfiles-methods.R'\n'updateObject-methods.R' 'utilities.R' 'zzz.R'", "Config/pak/sysreqs": "cmake libglpk-dev make libicu-dev libuv1-dev\nlibxml2-dev zlib1g-dev", 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