{
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  "Package": "Site2Target",
  "Type": "Package",
  "Title": "An R package to associate peaks and target genes",
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  "Authors@R": "person(\"Peyman Zarrineh\", email=\"peyman.zarrineh@manchester.ac.uk\", role=c(\"cre\", \"aut\"), comment = c(ORCID = \"0000-0003-4820-4101\"))",
  "Description": "Statistics implemented for both peak-wise and gene-wise\nassociations. In peak-wise associations, the p-value of the\ntarget genes of a given set of peaks are calculated. Negative\nbinomial or Poisson distributions can be used for modeling the\nunweighted peaks targets and log-nromal can be used to model\nthe weighted peaks. In gene-wise associations a table\nconsisting of a set of genes, mapped to specific peaks, is\ngenerated using the given rules.",
  "BugReports": "https://github.com/fls-bioinformatics-core/Site2Target/issues",
  "License": "GPL-2",
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  "Date/Publication": "2026-04-28 13:04:44 UTC",
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  "Author": "Peyman Zarrineh [cre, aut] (ORCID:\n<https://orcid.org/0000-0003-4820-4101>)",
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    "chipseq",
    "software",
    "epigenetics",
    "geneexpression",
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    "source": "https://www.bioconductor.org/packages/stats/bioc/Site2Target"
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    "extra/citation.json",
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  "_exports": [
    "addColumn2geneWiseAssociation",
    "addRelation2geneWiseAssociation",
    "extendSitesInGivenRegions",
    "genewiseAssociation",
    "getCenterOfPeaks",
    "getTargetGenesNumber",
    "getTargetGenesPvals",
    "getTargetGenesPvalsWithDNAInteractions",
    "getTargetGenesPvalsWithIntensities",
    "getTargetGenesPvalsWithIntensitiesAndDNAInteractions",
    "granges2String",
    "removeReserveCharacter",
    "string2Granges",
    "Table2Granges"
  ],
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    {
      "page": "addColumn2geneWiseAssociation",
      "title": "Add column to gene-wise association",
      "topics": [
        "addColumn2geneWiseAssociation"
      ]
    },
    {
      "page": "addRelation2geneWiseAssociation",
      "title": "Add a relation column to gene-peak interaction table",
      "topics": [
        "addRelation2geneWiseAssociation"
      ]
    },
    {
      "page": "data",
      "title": "MEIS cardiomyocytes datasets used in the package",
      "topics": [
        "data"
      ]
    },
    {
      "page": "extendSitesInGivenRegions",
      "title": "Extend sites given regions boundaries",
      "topics": [
        "extendSitesInGivenRegions"
      ]
    },
    {
      "page": "genewiseAssociation",
      "title": "Generate genewise association between genes and peaks",
      "topics": [
        "genewiseAssociation"
      ]
    },
    {
      "page": "getCenterOfPeaks",
      "title": "Return center of the given granges files",
      "topics": [
        "getCenterOfPeaks"
      ]
    },
    {
      "page": "getNameFromCoordinates",
      "title": "Get names of genes or peaks related to a query coordinates",
      "topics": [
        "getNameFromCoordinates"
      ]
    },
    {
      "page": "getTargetGenesNumber",
      "title": "generate number of sites per gene given distances",
      "topics": [
        "getTargetGenesNumber"
      ]
    },
    {
      "page": "getTargetGenesPvals",
      "title": "Fit Negative binomial distribution to target genes",
      "topics": [
        "getTargetGenesPvals"
      ]
    },
    {
      "page": "getTargetGenesPvalsWithDNAInteractions",
      "title": "Fit Negative binomial distribution to target genes",
      "topics": [
        "getTargetGenesPvalsWithDNAInteractions"
      ]
    },
    {
      "page": "getTargetGenesPvalsWithIntensities",
      "title": "Fit log-normal distribution to target genes",
      "topics": [
        "getTargetGenesPvalsWithIntensities"
      ]
    },
    {
      "page": "getTargetGenesPvalsWithIntensitiesAndDNAInteractions",
      "title": "Fit log-normal distribution to target genes",
      "topics": [
        "getTargetGenesPvalsWithIntensitiesAndDNAInteractions"
      ]
    },
    {
      "page": "granges2String",
      "title": "Convert granges to strings of coordinates",
      "topics": [
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      ]
    },
    {
      "page": "removeReserveCharacter",
      "title": "Remove reserved characters from a string",
      "topics": [
        "removeReserveCharacter"
      ]
    },
    {
      "page": "site2GeneDistance",
      "title": "Return the distance between paired peaks and genes",
      "topics": [
        "site2GeneDistance"
      ]
    },
    {
      "page": "Site2Target",
      "title": "Associate peaks and target genes",
      "topics": [
        "Site2Target"
      ]
    },
    {
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      ]
    },
    {
      "page": "Table2Granges",
      "title": "Take Genomic Ranges from a table file",
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      ]
    }
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      "modified": "2025-01-15 18:29:26",
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