{
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  "Package": "depmap",
  "Type": "Package",
  "Title": "Cancer Dependency Map Data Package",
  "Version": "1.26.0",
  "Authors@R": "c(person(given = \"Laurent\", family = \"Gatto\",\nemail = \"laurent.gatto@uclouvain.be\",\ncomment = c(ORCID = \"0000-0002-1520-2268\"),\nrole = c(\"cre\", \"aut\")),\nperson(given = \"Theo\", family = \"Killian\",\nrole = \"aut\"),\nperson(given = \"Alexander\", family = \"Peltzer\", role = \"ctb\",\ncomment = c(ORCID = \"0000-0002-6503-2180\")))",
  "Description": "The depmap package is a data package that accesses datsets\nfrom the Broad Institute DepMap cancer dependency study using\nExperimentHub. Datasets from the most current release are\navailable, including RNAI and CRISPR-Cas9 gene knockout screens\nquantifying the genetic dependency for select cancer cell\nlines. Additional datasets are also available pertaining to the\nlog copy number of genes for select cell lines, protein\nexpression of cell lines as measured by reverse phase protein\nlysate microarray (RPPA), 'Transcript Per Million' (TPM) data,\nas well as supplementary datasets which contain metadata and\nmutation calls for the other datasets found in the current\nrelease. The 19Q3 release adds the drug_dependency dataset,\nthat contains cancer cell line dependency data with respect to\ndrug and drug-candidate compounds. The 20Q2 release adds the\nproteomic dataset that contains quantitative profiling of\nproteins via mass spectrometry. This package will be updated on\na quarterly basis to incorporate the latest Broad Institute\nDepMap Public cancer dependency datasets. All data made\navailable in this package was generated by the Broad Institute\nDepMap for research purposes and not intended for clinical use.\nThis data is distributed under the Creative Commons license\n(Attribution 4.0 International (CC BY 4.0)).",
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  "Encoding": "UTF-8",
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  "biocViews": "ExperimentHub, ExperimentData, ReproducibleResearch,\nRepositoryData, AssayDomainData, CopyNumberVariationData,\nDiseaseModel, CancerData, BreastCancerData, ColonCancerData,\nKidneyCancerData, LeukemiaCancerData, LungCancerData,\nOvarianCancerData, ProstateCancerData, OrganismData,\nHomo_sapiens_Data, PackageTypeData, SpecimenSource,\nCellCulture, Genome, Proteome, StemCell, Tissue",
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  "Repository": "Bioconductor 3.23",
  "Date/Publication": "2026-04-28 12:33:14 UTC",
  "RemoteUrl": "https://github.com/bioc/depmap",
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    "User": "root"
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  "Author": "Laurent Gatto [cre, aut] (ORCID:\n<https://orcid.org/0000-0002-1520-2268>),\nTheo Killian [aut],\nAlexander Peltzer [ctb] (ORCID:\n<https://orcid.org/0000-0002-6503-2180>)",
  "Maintainer": "Laurent Gatto <laurent.gatto@uclouvain.be>",
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  "_created": "2026-10-10T11:16:12.000Z",
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    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
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    "repositorydata",
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    "copynumbervariationdata",
    "diseasemodel",
    "cancerdata",
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    "coloncancerdata",
    "kidneycancerdata",
    "leukemiacancerdata",
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    "ovariancancerdata",
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    "homo_sapiens_data",
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      "title": "achilles_22Q2",
      "topics": [
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        "achilles_22Q1",
        "achilles_22Q2",
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        "copyNumber_19Q1",
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      "page": "crispr",
      "title": "crispr_22Q2",
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        "crispr_19Q2",
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        "crispr_19Q4",
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        "crispr_21Q2",
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    {
      "page": "depmap",
      "title": "depmap: Cancer Dependency Map Data Package",
      "topics": [
        "depmap-package",
        "depmap"
      ]
    },
    {
      "page": "depmap_release",
      "title": "Returns the depmap release",
      "topics": [
        "depmap_release"
      ]
    },
    {
      "page": "DepMapFiles",
      "title": "DepMap Dataset and Files",
      "topics": [
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        "dmfiles",
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        "dmsets",
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      ]
    },
    {
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      "title": "Depmap Package Cache",
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      ]
    },
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      "title": "drug_sensitivity_21Q2",
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    },
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      "page": "gene_summary",
      "title": "gene_summary_22Q1",
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    },
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        "metadata_19Q1",
        "metadata_19Q2",
        "metadata_19Q3",
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        "metadata_20Q1",
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        "mutationCalls_19Q2",
        "mutationCalls_19Q3",
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        "proteomic",
        "proteomic_20Q2"
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    },
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      "title": "rnai_19Q3",
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    },
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        "RPPA_19Q1",
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      "title": "The depmap data",
      "author": "Theo Killian, Laurent Gatto",
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        "CCLE Reverse Phase Protein Array data",
        "CCLE RNAseq gene expression data",
        "Cancer cell lines",
        "Mutation calls",
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      "created": "2019-03-19 08:41:11",
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