{ "_id": "6a1ae4a11d7bb097a09efb87", "Package": "epimutacions", "Title": "Robust outlier identification for DNA methylation data", "Version": "1.16.0", "Authors@R": "c(person(\"Dolors\", \"Pelegri-Siso\", ,\"dolors.pelegri@isglobal.org\", role = c(\"aut\", \"cre\"),comment = c(ORCID = \"0000-0002-5993-3003\")),\nperson(\"Juan R.\", \"Gonzalez\", ,\"juanr.gonzalez@isglobal.org\", role = \"aut\", comment = c(ORCID = \"0000-0003-3267-2146\")),\nperson(\"Carlos\", \"Ruiz-Arenas\", ,\"carlos.ruiza@upf.edu\", role = \"aut\", comment = c(ORCID = \"0000-0002-6014-3498\")),\nperson(\"Carles\", \"Hernandez-Ferrer\", ,\"carles.hernandez@cnag.crg.eu\", role = \"aut\", comment = c(ORCID = \"0000-0002-8029-7160\")),\nperson(\"Leire\",family = \"Abarrategui\",role = c(\"aut\"),email = \"abarrategui.leire@gmail.com\", comment = c(ORCID = \"0000-0002-1175-038X\")))", "Description": "The package includes some statistical outlier detection\nmethods for epimutations detection in DNA methylation data. The\nmethods included in the package are MANOVA, Multivariate linear\nmodels, isolation forest, robust mahalanobis distance, quantile\nand beta. The methods compare a case sample with a suspected\ndisease against a reference panel (composed of healthy\nindividuals) to identify epimutations in the given case sample.\nIt also contains functions to annotate and visualize the\nidentified epimutations.", "biocViews": "DNAMethylation, BiologicalQuestion, Preprocessing,\nStatisticalMethod, Normalization", "License": "MIT + file LICENSE", "VignetteBuilder": "knitr", "Encoding": "UTF-8", "Roxygen": "list(markdown = TRUE)", "URL": "https://github.com/isglobal-brge/epimutacions", "BugReports": "https://github.com/isglobal-brge/epimutacions/issues", "RoxygenNote": "7.2.3", "Config/pak/sysreqs": "cmake make libbz2-dev libicu-dev libjpeg-dev\nliblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev\nlibx11-dev xz-utils zlib1g-dev", "Repository": "https://bioc-release.r-universe.dev", "Date/Publication": "2026-04-28 12:58:12 UTC", "RemoteUrl": "https://github.com/bioc/epimutacions", "RemoteRef": "RELEASE_3_23", "RemoteSha": "bd909c75318c4980e9c921e2510bf27c056ba3bc", "NeedsCompilation": "yes", "Packaged": { "Date": "2026-05-30 09:16:41 UTC", "User": "root" }, "Author": "Dolors Pelegri-Siso [aut, cre] (ORCID:\n),\nJuan R. 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