{
  "_id": "6a1949dfacfb0bcc41ddbfcf",
  "Package": "goProfiles",
  "Version": "1.74.0",
  "Title": "goProfiles: an R package for the statistical analysis of\nfunctional profiles",
  "Author": "Alex Sanchez, Jordi Ocana and Miquel Salicru",
  "Type": "Package",
  "Date": "2018-04-20",
  "Maintainer": "Alex Sanchez <asanchez@ub.edu>",
  "Description": "The package implements methods to compare lists of genes\nbased on comparing the corresponding 'functional profiles'.",
  "License": "GPL-2",
  "biocViews": "Annotation, GO, GeneExpression, GeneSetEnrichment,\nGraphAndNetwork, Microarray, MultipleComparison, Pathways,\nSoftware",
  "url": "https://github.com/alexsanchezpla/goProfiles/wiki",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-05-29 07:05:29 UTC",
    "User": "root"
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  "RoxygenNote": "6.0.1",
  "Config/pak/sysreqs": "libicu-dev libpng-dev libssl-dev zlib1g-dev",
  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 12:32:52 UTC",
  "RemoteUrl": "https://github.com/bioc/goProfiles",
  "RemoteRef": "RELEASE_3_23",
  "RemoteSha": "d3ff44c396972fcd3c19243b06ec225dc7be8601",
  "MD5sum": "c1294c3c313d0d44fa6fa56dfa0ddeb5",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "goProfiles_1.74.0.tar.gz",
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  "_created": "2026-05-29T07:05:29.000Z",
  "_published": "2026-05-29T08:10:07.449Z",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
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    "name": "Alex Sanchez",
    "email": "asanchez@ub.edu",
    "login": "alexsanchezpla",
    "description": "",
    "uuid": 13941769
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  "_registered": true,
  "_dependencies": [
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      "package": "Biobase",
      "role": "Depends"
    },
    {
      "package": "AnnotationDbi",
      "role": "Depends"
    },
    {
      "package": "GO.db",
      "role": "Depends"
    },
    {
      "package": "CompQuadForm",
      "role": "Depends"
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      "package": "stringr",
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      "role": "Suggests"
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  ],
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    "go",
    "geneexpression",
    "genesetenrichment",
    "graphandnetwork",
    "microarray",
    "multiplecomparison",
    "pathways",
    "software"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
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    "source": "https://www.bioconductor.org/packages/stats/bioc/goProfiles"
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  "_mentions": 10,
  "_searchresults": 6,
  "_rbuild": "4.6.0",
  "_assets": [
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    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/goProfiles.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "as.GOTerms.frame",
    "as.GOTerms.list",
    "basicProfile",
    "BioCpack2EntrezIDS",
    "BioCpack2Profiles",
    "BioCprobes2Entrez",
    "compareGeneLists",
    "compareGOProfiles",
    "compareProfilesLists",
    "compSummary",
    "contractedProfile",
    "equivalentGOProfiles",
    "equivClust",
    "equivClust2pdf",
    "equivSummary",
    "expandedLevel",
    "expandedProfile",
    "expandTerm",
    "fisherGOProfiles",
    "fitGOProfile",
    "getAncestorsLst",
    "getGOLevel",
    "GOTermsFrame2GOTermsList",
    "GOTermsList",
    "iterEquivClust",
    "mergeProfilesLists",
    "ngenes",
    "plotProfiles",
    "printProfiles"
  ],
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    {
      "name": "CD4LLids",
      "title": "Entrez identifiers for CD4-TCells example",
      "object": "CD4Ids",
      "file": "CD4Ids.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "clustKidneyMF2",
      "title": "Ready 2 cluster equivalence distance matrix obtained from the analysis of the \"Kidney Dataset\" at level 2 of the MF ontology",
      "object": "clustKidneyMF2",
      "file": "clustKidneyMF2.rda",
      "class": [
        "equivClust",
        "hclust"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    },
    {
      "name": "diseaseIds",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "dominantIds",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "dominantIdsEBI",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "dominantIdsNCBI",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "drosophilaIds",
      "title": "Entrez identifiers for genes related with an eye mutation in drosophila",
      "object": "drosophila",
      "file": "drosophila.rda",
      "class": [
        "integer"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "hugoIds",
      "title": "Entrez Identifiers obtained from the Human Genome Organization",
      "object": "hugoIds",
      "file": "hugoIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "kidneyGeneLists",
      "title": "Gene-lists related to kidney transplantation rejection",
      "object": "kidneyGeneLists",
      "file": "kidneyGeneLists.rda",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "michaudIds",
      "title": "Entrez identifiers for genes related with an eye mutation in drosophila",
      "object": "drosophila",
      "file": "drosophila.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "morbidmapIds",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "ostrinIds",
      "title": "Entrez identifiers for genes related with an eye mutation in drosophila",
      "object": "drosophila",
      "file": "drosophila.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "recessiveIds",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "recessiveIdsEBI",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "recessiveIdsNCBI",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "object": "omimIds",
      "file": "omimIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "singh01EntrezIDs",
      "title": "Prostate cancer-related genes",
      "object": "prostateIds",
      "file": "prostateIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "singh05EntrezIDs",
      "title": "Prostate cancer-related genes",
      "object": "prostateIds",
      "file": "prostateIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "welsh01EntrezIDs",
      "title": "Prostate cancer-related genes",
      "object": "prostateIds",
      "file": "prostateIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "welsh05EntrezIDs",
      "title": "Prostate cancer-related genes",
      "object": "prostateIds",
      "file": "prostateIds.rda",
      "class": [
        "character"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "goProfiles-package",
      "title": "Performs Gene Ontology based analysis using Functional Profiles.",
      "topics": [
        "goProfiles-package",
        "goProfiles"
      ]
    },
    {
      "page": "basicProfile",
      "title": "Builds basic functional profile",
      "topics": [
        "basicProfile"
      ]
    },
    {
      "page": "CD4ids",
      "title": "Entrez identifiers for CD4-TCells example",
      "topics": [
        "CD4GOTermsFrame",
        "CD4GOTermsList",
        "CD4LLids"
      ]
    },
    {
      "page": "clustKidneyMF2",
      "title": "Ready 2 cluster equivalence distance matrix obtained from the analysis of the \"Kidney Dataset\" at level 2 of the MF ontology",
      "topics": [
        "clustKidneyMF2"
      ]
    },
    {
      "page": "compareGeneLists",
      "title": "Compares two lists of genes by building (expanded) profiles and comparing them",
      "topics": [
        "compareGeneLists"
      ]
    },
    {
      "page": "compareGOProfiles",
      "title": "Comparison of lists of genes through their functional profiles",
      "topics": [
        "compareGOProfiles"
      ]
    },
    {
      "page": "compareProfilesLists",
      "title": "Compares two of expanded profiles",
      "topics": [
        "compareProfilesLists"
      ]
    },
    {
      "page": "compSummary",
      "title": "This function returns a brief summary of the comparison between two (expanded) profiles.",
      "topics": [
        "compSummary"
      ]
    },
    {
      "page": "contractedProfile",
      "title": "Converts an expanded GO profile into a basic (contracted) GO profile",
      "topics": [
        "contractedProfile",
        "contractedProfile.default",
        "contractedProfile.ExpandedGOProfile"
      ]
    },
    {
      "page": "conversionFunctions",
      "title": "Functions to transformconvert objects between different types",
      "topics": [
        "as.GOTerms.frame",
        "as.GOTerms.list",
        "BioCpack2EntrezIDS",
        "BioCpack2Profiles",
        "BioCprobes2Entrez",
        "GOTermsFrame2GOTermsList"
      ]
    },
    {
      "page": "drosophila",
      "title": "Entrez identifiers for genes related with an eye mutation in drosophila",
      "topics": [
        "drosophilaIds",
        "michaudIds",
        "ostrinIds"
      ]
    },
    {
      "page": "equivalentGOProfiles",
      "title": "Are two lists of genes equivalent in terms of their Gene Ontology profiles?",
      "topics": [
        "equivalentGOProfiles",
        "equivalentGOProfiles.default",
        "equivalentGOProfiles.ExpandedGOProfile",
        "equivalentGOProfiles.GOProfileHtest"
      ]
    },
    {
      "page": "equivClust",
      "title": "For a given level (2, 3, ...) in a GO ontology (BP, MF or CC), compute the equivalence threshold distance matrix and generate a dendrogram from it.",
      "topics": [
        "equivClust"
      ]
    },
    {
      "page": "equivClust2pdf",
      "title": "Save the graphical representation of objects of class 'equivClust' or 'iterEquivClust' as pdf files.",
      "topics": [
        "equivClust2pdf",
        "equivClust2pdf.equivClust",
        "equivClust2pdf.iterEquivClust"
      ]
    },
    {
      "page": "equivSummary",
      "title": "This function returns a brief summary of the equivalence test between two profiles.",
      "topics": [
        "equivSummary"
      ]
    },
    {
      "page": "expandedLevel",
      "title": "Function to create expanded levels which can contain GO Terms at different GO levels",
      "topics": [
        "expandedLevel",
        "expandTerm"
      ]
    },
    {
      "page": "expandedProfile",
      "title": "Builds expanded profiles",
      "topics": [
        "expandedProfile"
      ]
    },
    {
      "page": "fisherGOProfiles",
      "title": "GO Class-by-class Fisher tests in lists of genes characterized by their functional profiles",
      "topics": [
        "fisherGOProfiles",
        "fisherGOProfiles.BasicGOProfile",
        "fisherGOProfiles.ExpandedGOProfile",
        "fisherGOProfiles.matrix",
        "fisherGOProfiles.numeric"
      ]
    },
    {
      "page": "fitGOProfile",
      "title": "Does a \"sample\" GO profile 'pn', observed in a sample of 'n' genes, fit a \"population\" or \"model\" p0?",
      "topics": [
        "fitGOProfile"
      ]
    },
    {
      "page": "GOTermsList",
      "title": "Functions to create and manage lists of GO terms associated with a vector of 'Entrez' identifiers",
      "topics": [
        "getAncestorsLst",
        "getGOLevel",
        "GOTermsList"
      ]
    },
    {
      "page": "hugoIds",
      "title": "Entrez Identifiers obtained from the Human Genome Organization",
      "topics": [
        "hugoIds"
      ]
    },
    {
      "page": "iterEquivClust",
      "title": "For each combination of the specified levels in the choosen GO ontologies, compute the equivalence threshold distance matrix and generate a dendrogram from it.",
      "topics": [
        "iterEquivClust"
      ]
    },
    {
      "page": "kidneyGeneLists",
      "title": "Gene-lists related to kidney transplantation rejection",
      "topics": [
        "kidneyGeneLists"
      ]
    },
    {
      "page": "mergeProfilesLists",
      "title": "Combines two lists of profiles into one",
      "topics": [
        "mergeProfilesLists"
      ]
    },
    {
      "page": "ngenes",
      "title": "Returns the number of genes that lead to this GO profile (an object of class ExpandedGOProfile, BasicGOProfile or assimilable to them)",
      "topics": [
        "ngenes",
        "ngenes.BasicGOProfile",
        "ngenes.default",
        "ngenes.ExpandedGOProfile",
        "ngenes.matrix",
        "ngenes.numeric"
      ]
    },
    {
      "page": "omimIds",
      "title": "Entrez identifiers for disease-related genes in the OMIM database",
      "topics": [
        "diseaseIds",
        "dominantIds",
        "dominantIdsEBI",
        "dominantIdsNCBI",
        "morbidmapIds",
        "omimIds",
        "recessiveIds",
        "recessiveIdsEBI",
        "recessiveIdsNCBI"
      ]
    },
    {
      "page": "plotProfiles",
      "title": "Plot functional profiles",
      "topics": [
        "plotProfiles"
      ]
    },
    {
      "page": "printProfiles",
      "title": "Print functional profiles",
      "topics": [
        "printProfiles"
      ]
    },
    {
      "page": "prostateIds",
      "title": "Prostate cancer-related genes",
      "topics": [
        "prostateIds",
        "singh01EntrezIDs",
        "singh05EntrezIDs",
        "welsh01EntrezIDs",
        "welsh05EntrezIDs"
      ]
    }
  ],
  "_readme": "https://github.com/bioc/goProfiles/raw/RELEASE_3_23/README.md",
  "_rundeps": [
    "AnnotationDbi",
    "askpass",
    "Biobase",
    "BiocGenerics",
    "Biostrings",
    "bit",
    "bit64",
    "blob",
    "cachem",
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    "crayon",
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    "DBI",
    "fastmap",
    "generics",
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    "IRanges",
    "jsonlite",
    "KEGGREST",
    "lifecycle",
    "magrittr",
    "memoise",
    "mime",
    "openssl",
    "pkgconfig",
    "png",
    "R6",
    "rlang",
    "RSQLite",
    "S4Vectors",
    "Seqinfo",
    "stringi",
    "stringr",
    "sys",
    "vctrs",
    "XVector"
  ],
  "_vignettes": [
    {
      "source": "goProfiles.Rnw",
      "filename": "goProfiles.pdf",
      "title": "goProfiles Vignette",
      "engine": "utils::Sweave",
      "headings": [],
      "created": "2017-10-17 15:50:36",
      "modified": "2018-04-17 10:58:34",
      "commits": 3
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  ],
  "_score": 5.477121254719663,
  "_indexed": false,
  "_nocasepkg": "goprofiles",
  "_universes": [
    "bioc-release"
  ],
  "_indexurl": "https://bioc.r-universe.dev/goProfiles",
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