{
  "_id": "6a194bafacfb0bcc41ddcdde",
  "Package": "metaCCA",
  "Type": "Package",
  "Title": "Summary Statistics-Based Multivariate Meta-Analysis of\nGenome-Wide Association Studies Using Canonical Correlation\nAnalysis",
  "Version": "1.40.0",
  "Date": "2016-01-26",
  "Author": "Anna Cichonska <anna.cichonska@gmail.com>",
  "Maintainer": "Anna Cichonska <anna.cichonska@gmail.com>",
  "VignetteBuilder": "knitr",
  "Description": "metaCCA performs multivariate analysis of a single or\nmultiple GWAS based on univariate regression coefficients. It\nallows multivariate representation of both phenotype and\ngenotype. metaCCA extends the statistical technique of\ncanonical correlation analysis to the setting where original\nindividual-level records are not available, and employs a\ncovariance shrinkage algorithm to achieve robustness.",
  "License": "MIT + file LICENSE",
  "URL": "https://doi.org/10.1093/bioinformatics/btw052",
  "LazyData": "TRUE",
  "biocViews": "GenomeWideAssociation, SNP, Genetics, Regression,\nStatisticalMethod, Software",
  "NeedsCompilation": "no",
  "Repository": "https://bioc-release.r-universe.dev",
  "Date/Publication": "2026-04-28 12:42:38 UTC",
  "RemoteUrl": "https://github.com/bioc/metaCCA",
  "RemoteRef": "RELEASE_3_23",
  "RemoteSha": "019bc50147034fde4a7efde46d9836aad09df2ce",
  "Packaged": {
    "Date": "2026-05-29 07:14:03 UTC",
    "User": "root"
  },
  "MD5sum": "75d11094f51e9fa536f5fb81c1c3c6e3",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "metaCCA_1.40.0.tar.gz",
  "_fileid": "70ed59b2e6a13dc752ec49fbee26a0f665ec5c2418eac281482eb88b9d1866b5",
  "_filesize": 1071012,
  "_sha256": "70ed59b2e6a13dc752ec49fbee26a0f665ec5c2418eac281482eb88b9d1866b5",
  "_created": "2026-05-29T07:14:03.000Z",
  "_published": "2026-05-29T08:17:51.303Z",
  "_jobs": [
    {
      "job": 78455298455,
      "time": 115,
      "config": "bioc-checks",
      "r": "4.6.0",
      "check": "ERROR",
      "artifact": "7285184366"
    },
    {
      "job": 78455298531,
      "time": 153,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7285195512"
    },
    {
      "job": 78455298516,
      "time": 151,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7285194828"
    },
    {
      "job": 78455298637,
      "time": 98,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7286227592"
    },
    {
      "job": 78455298608,
      "time": 66,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7286217536"
    },
    {
      "job": 78454979312,
      "time": 148,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7285153135"
    },
    {
      "job": 78455298482,
      "time": 82,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7285176047"
    },
    {
      "job": 78455298450,
      "time": 66,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "WARNING",
      "artifact": "7285171549"
    },
    {
      "job": 78455298460,
      "time": 74,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "WARNING",
      "artifact": "7285174413"
    },
    {
      "job": 78455298464,
      "time": 74,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "WARNING",
      "artifact": "7285173647"
    }
  ],
  "_bioccheck": {
    "error": 1,
    "warning": 2,
    "note": 14
  },
  "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/bioc/metaCCA",
  "_commit": {
    "id": "019bc50147034fde4a7efde46d9836aad09df2ce",
    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
    "time": 1777380158
  },
  "_maintainer": {
    "name": "Anna Cichonska",
    "email": "anna.cichonska@gmail.com",
    "login": "acichonska",
    "description": "",
    "uuid": 13220144
  },
  "_distro": "noble",
  "_registered": true,
  "_dependencies": [
    {
      "package": "knitr",
      "role": "Suggests"
    }
  ],
  "_owner": "bioc",
  "_selfowned": false,
  "_usedby": 0,
  "_updates": [
    {
      "week": "2025-44",
      "n": 2
    },
    {
      "week": "2026-18",
      "n": 1
    }
  ],
  "_tags": [],
  "_bioc": [
    {
      "branch": "devel",
      "version": "1.41.0",
      "bioc": "3.24"
    },
    {
      "branch": "release",
      "version": "1.40.0",
      "bioc": "3.23"
    }
  ],
  "_topics": [
    "genomewideassociation",
    "snp",
    "genetics",
    "regression",
    "statisticalmethod",
    "software"
  ],
  "_userbio": {
    "uuid": 2286807,
    "type": "organization",
    "name": "Bioconductor",
    "description": "Software for the analysis and comprehension of high-throughput genomic data"
  },
  "_downloads": {
    "count": 326,
    "source": "https://www.bioconductor.org/packages/stats/bioc/metaCCA"
  },
  "_mentions": 9,
  "_searchresults": 9,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/metaCCA.html",
    "manual.pdf"
  ],
  "_realowner": "bioc",
  "_cranurl": false,
  "_exports": [
    "estimateSyy",
    "metaCcaGp",
    "metaCcaPlusGp"
  ],
  "_datasets": [
    {
      "name": "N1",
      "title": "Number of individuals in study 1.",
      "object": "testDataMetaCCA",
      "class": [
        "numeric"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "N2",
      "title": "Number of individuals in study 2.",
      "object": "testDataMetaCCA",
      "class": [
        "numeric"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "S_XX_study1",
      "title": "Correlations between 10 SNPs corresponding to the population underlying study 1.",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "rs10",
        "rs80",
        "rs140",
        "rs170",
        "rs172",
        "rs174",
        "rs176",
        "rs178",
        "rs180",
        "rs200"
      ],
      "rows": 10,
      "table": true,
      "tojson": true
    },
    {
      "name": "S_XX_study2",
      "title": "Correlations between 10 SNPs corresponding to the population underlying study 2.",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "rs10",
        "rs80",
        "rs140",
        "rs170",
        "rs172",
        "rs174",
        "rs176",
        "rs178",
        "rs180",
        "rs200"
      ],
      "rows": 10,
      "table": true,
      "tojson": true
    },
    {
      "name": "S_XY_full_study1",
      "title": "Univariate summary statistics of 10 traits across 1000 SNPs (study 1).",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "allele_0",
        "allele_1",
        "trait1_b",
        "trait1_se",
        "trait2_b",
        "trait2_se",
        "trait3_b",
        "trait3_se",
        "trait4_b",
        "trait4_se",
        "trait5_b",
        "trait5_se",
        "trait6_b",
        "trait6_se",
        "trait7_b",
        "trait7_se",
        "trait8_b",
        "trait8_se",
        "trait9_b",
        "trait9_se",
        "trait10_b",
        "trait10_se"
      ],
      "rows": 1000,
      "table": true,
      "tojson": true
    },
    {
      "name": "S_XY_full_study2",
      "title": "Univariate summary statistics of 10 traits across 1000 SNPs (study 2).",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "allele_0",
        "allele_1",
        "trait1_b",
        "trait1_se",
        "trait2_b",
        "trait2_se",
        "trait3_b",
        "trait3_se",
        "trait4_b",
        "trait4_se",
        "trait5_b",
        "trait5_se",
        "trait6_b",
        "trait6_se",
        "trait7_b",
        "trait7_se",
        "trait8_b",
        "trait8_se",
        "trait9_b",
        "trait9_se",
        "trait10_b",
        "trait10_se"
      ],
      "rows": 1000,
      "table": true,
      "tojson": true
    },
    {
      "name": "S_XY_study1",
      "title": "Univariate summary statistics of 10 traits across 10 SNPs (study 1).",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "allele_0",
        "allele_1",
        "trait1_b",
        "trait1_se",
        "trait2_b",
        "trait2_se",
        "trait3_b",
        "trait3_se",
        "trait4_b",
        "trait4_se",
        "trait5_b",
        "trait5_se",
        "trait6_b",
        "trait6_se",
        "trait7_b",
        "trait7_se",
        "trait8_b",
        "trait8_se",
        "trait9_b",
        "trait9_se",
        "trait10_b",
        "trait10_se"
      ],
      "rows": 10,
      "table": true,
      "tojson": true
    },
    {
      "name": "S_XY_study2",
      "title": "Univariate summary statistics of 10 traits across 10 SNPs (study 2).",
      "object": "testDataMetaCCA",
      "class": [
        "data.frame"
      ],
      "fields": [
        "allele_0",
        "allele_1",
        "trait1_b",
        "trait1_se",
        "trait2_b",
        "trait2_se",
        "trait3_b",
        "trait3_se",
        "trait4_b",
        "trait4_se",
        "trait5_b",
        "trait5_se",
        "trait6_b",
        "trait6_se",
        "trait7_b",
        "trait7_se",
        "trait8_b",
        "trait8_se",
        "trait9_b",
        "trait9_se",
        "trait10_b",
        "trait10_se"
      ],
      "rows": 10,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "estimateSyy",
      "title": "Function to estimate correlations between phenotypic variables from summary statistics",
      "topics": [
        "estimateSyy"
      ]
    },
    {
      "page": "metaCcaGp",
      "title": "Function to perform genotype-phenotype association analysis according to metaCCA algorithm.",
      "topics": [
        "metaCcaGp"
      ]
    },
    {
      "page": "metaCcaPlusGp",
      "title": "Function to perform genotype-phenotype association analysis according to metaCCA+ algorithm.",
      "topics": [
        "metaCcaPlusGp"
      ]
    },
    {
      "page": "N1",
      "title": "Number of individuals in study 1.",
      "topics": [
        "N1"
      ]
    },
    {
      "page": "N2",
      "title": "Number of individuals in study 2.",
      "topics": [
        "N2"
      ]
    },
    {
      "page": "S_XX_study1",
      "title": "Correlations between 10 SNPs corresponding to the population underlying study 1.",
      "topics": [
        "S_XX_study1"
      ]
    },
    {
      "page": "S_XX_study2",
      "title": "Correlations between 10 SNPs corresponding to the population underlying study 2.",
      "topics": [
        "S_XX_study2"
      ]
    },
    {
      "page": "S_XY_full_study1",
      "title": "Univariate summary statistics of 10 traits across 1000 SNPs (study 1).",
      "topics": [
        "S_XY_full_study1"
      ]
    },
    {
      "page": "S_XY_full_study2",
      "title": "Univariate summary statistics of 10 traits across 1000 SNPs (study 2).",
      "topics": [
        "S_XY_full_study2"
      ]
    },
    {
      "page": "S_XY_study1",
      "title": "Univariate summary statistics of 10 traits across 10 SNPs (study 1).",
      "topics": [
        "S_XY_study1"
      ]
    },
    {
      "page": "S_XY_study2",
      "title": "Univariate summary statistics of 10 traits across 10 SNPs (study 2).",
      "topics": [
        "S_XY_study2"
      ]
    }
  ],
  "_rundeps": [],
  "_vignettes": [
    {
      "source": "metaCCA.Rnw",
      "filename": "metaCCA.pdf",
      "title": "metaCCA",
      "engine": "knitr::knitr",
      "headings": [],
      "created": "2016-02-18 22:39:17",
      "modified": "2019-06-23 19:10:53",
      "commits": 2
    }
  ],
  "_score": 4.2552725051033065,
  "_indexed": false,
  "_nocasepkg": "metacca",
  "_universes": [
    "bioc-release"
  ],
  "_indexurl": "https://bioc.r-universe.dev/metaCCA",
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.40.0",
      "date": "2026-05-29T07:16:41.000Z",
      "distro": "noble",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "de6940608c1eb7ed34178d7be721366a244bd59e621d43f5f6aed49c82e490c4",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.40.0",
      "date": "2026-05-29T07:16:40.000Z",
      "distro": "noble",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "881a7fe8483c579a44a24dc9be54d41e5fed6db297c72f3b8814a337abb9171f",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.40.0",
      "date": "2026-05-29T08:17:22.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "b3034939fd5bfd922280eb7fa062c441d207bcd7e9dc3655785d436d0f20f7ef",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.40.0",
      "date": "2026-05-29T08:16:48.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "47139d9c95a59072ce68bedb132db6fe4c96cf26e45e8dc58199f457fdb1b729",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.40.0",
      "date": "2026-05-29T07:15:42.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "b6cd6206c27626c30c9b0fa110546955da724232804a2b30635dff695f4a6f4b",
      "status": "success",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.40.0",
      "date": "2026-05-29T07:15:10.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "8106ac4f082926a5a404b48fb0308c179cca94488a4c4530478f3a365288d437",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.40.0",
      "date": "2026-05-29T07:15:20.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "2994d766ed97cea30680dc6be287695856a4a70014ed536bccbe8b99bc015530",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.40.0",
      "date": "2026-05-29T07:15:15.000Z",
      "commit": "019bc50147034fde4a7efde46d9836aad09df2ce",
      "fileid": "3fe95b8546dfc56f648c1b79c74db65f17e8b52a0af1b3a23c54b16263ec6505",
      "status": "success",
      "check": "WARNING",
      "buildurl": "https://github.com/r-universe/bioc-release/actions/runs/26623594727"
    }
  ]
}