{
  "_id": "6ad1f1c329625c14e47af2ad",
  "Package": "multicrispr",
  "Title": "Multi-locus multi-purpose Crispr/Cas design",
  "Version": "1.22.0",
  "Encoding": "UTF-8",
  "Authors@R": "c(person(\"Aditya\",   \"Bhagwat\",    NULL, \"aditya.bhagwat@uni-marburg.de\",   c(\"aut\", \"cre\")),\nperson( \"Richie\",   \"´Cotton\",    NULL, \"richierocks@gmail.com\",            \"aut\"),\nperson( \"Rene\",     \"Wiegandt\",   NULL, \"rene.wiegandt@mpi-bn.mpg.de\",      \"ctb\"),\nperson( \"Mette\",    \"Bentsen\",    NULL, \"mette.bentsen@mpi-bn.mpg.de\",      \"ctb\"),\nperson( \"Jens\",     \"Preussner\",  NULL, \"jens.preussner@mpi-bn.mpg.de\",     \"ctb\"),\nperson( \"Michael\",  \"Lawrence\",   NULL, \"lawrence.michael@gene.com\",        \"ctb\"),\nperson( \"Hervé\",    \"Pagès\",      NULL, \"hpages.on.github@gmail.com\",       \"ctb\"),\nperson( \"Johannes\", \"Graumann\",   NULL, 'johannes.graumann@uni-marburg.de', \"sad\"),\nperson( \"Mario\",    \"Looso\",      NULL, \"mario.looso@mpi-bn.mpg.de\",        c(\"sad\",\"rth\")))",
  "Description": "This package is for designing Crispr/Cas9 and Prime\nEditing experiments. It contains functions to (1) define and\ntransform genomic targets, (2) find spacers (4) count offtarget\n(mis)matches, and (5) compute Doench2016/2014 targeting\nefficiency. Care has been taken for multicrispr to scale well\ntowards large target sets, enabling the design of large\nCrispr/Cas9 libraries.",
  "License": "GPL-2",
  "RoxygenNote": "7.3.2",
  "VignetteBuilder": "knitr",
  "biocViews": "CRISPR, Software",
  "BugReports": "https://github.com/bhagwataditya/multicrispr/issues",
  "URL": "https://github.com/bhagwataditya/multicrispr",
  "Config/pak/sysreqs": "cmake make libbz2-dev libicu-dev liblzma-dev\nlibpng-dev libuv1-dev libxml2-dev libssl-dev python3 libx11-dev\nxz-utils zlib1g-dev",
  "Repository": "Bioconductor 3.23",
  "Date/Publication": "2026-04-28 12:52:55 UTC",
  "RemoteUrl": "https://github.com/bioc/multicrispr",
  "RemoteRef": "RELEASE_3_23",
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  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-16 08:28:13 UTC",
    "User": "root"
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  "Author": "Aditya Bhagwat [aut, cre],\nRichie ´Cotton [aut],\nRene Wiegandt [ctb],\nMette Bentsen [ctb],\nJens Preussner [ctb],\nMichael Lawrence [ctb],\nHervé Pagès [ctb],\nJohannes Graumann [sad],\nMario Looso [sad, rth]",
  "Maintainer": "Aditya Bhagwat <aditya.bhagwat@uni-marburg.de>",
  "_user": "bioc-release",
  "_type": "src",
  "_file": "multicrispr_1.22.0.tar.gz",
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  "_expires": "2027-01-24T09:43:29.000Z",
  "_created": "2026-10-16T08:28:13.000Z",
  "_published": "2026-10-16T09:43:31.078Z",
  "_buildurl": "https://github.com/r-universe/bioc-release/actions/runs/38873019329",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_bioccheck": {
    "error": 0,
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    "note": 7
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  "_upstream": "https://github.com/bioc/multicrispr",
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    "author": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "committer": "A Wokaty <andres.wokaty@sph.cuny.edu>",
    "message": "bump x.y.z version to even y prior to creation of RELEASE_3_23 branch\n",
    "time": 1777380775
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  "_maintainer": {
    "name": "Aditya Bhagwat",
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    "double_flank",
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    "genefile_to_granges",
    "genes_to_granges",
    "gr2dt",
    "has_been_indexed",
    "index_genome",
    "index_targets",
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    "score_ontargets",
    "up_flank",
    "write_ranges"
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      "page": "add_genome_matches",
      "title": "Add genome matches",
      "topics": [
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      "page": "add_inverse_strand",
      "title": "Add inverse strand",
      "topics": [
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      ]
    },
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      "title": "Add sequence to GRanges",
      "topics": [
        "add_seq"
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    },
    {
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      "title": "Add target matches",
      "topics": [
        "add_target_matches"
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    {
      "page": "bed_to_granges",
      "title": "Read bedfile into GRanges",
      "topics": [
        "bed_to_granges"
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    },
    {
      "page": "char_to_granges",
      "title": "Convert character vector into GRanges",
      "topics": [
        "char_to_granges"
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    },
    {
      "page": "double_flank",
      "title": "Double flank",
      "topics": [
        "double_flank"
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    {
      "page": "extend_for_pe",
      "title": "Extend ranges for prime editing",
      "topics": [
        "extend_for_pe"
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    },
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      "page": "extend_pe_to_gg",
      "title": "Extend prime editing target to find GG sites",
      "topics": [
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      "page": "extract_matchranges",
      "title": "Extract matching subranges",
      "topics": [
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      "title": "Extract subranges",
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      "page": "find_primespacers",
      "title": "Find prime editing spacers",
      "topics": [
        "find_primespacers"
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      "page": "find_spacers",
      "title": "Find crispr spacers in targetranges",
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      "topics": [
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        "genes_to_granges"
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        "gr2dt"
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      "title": "Has been indexed?",
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      "author": "Aditya M Bhagwat",
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