Package: cfDNAPro Type: Package Title: cfDNAPro extracts and Visualises biological features from whole genome sequencing data of cell-free DNA Version: 1.18.0 biocViews: Visualization, Sequencing, WholeGenome Authors@R: c( person("Haichao","Wang", email="hw538@cam.ac.uk", role =c("aut","cre")), person("Hui","Zhao", email="hui.zhao@cruk.cam.ac.uk", role =c("ctb")), person("Elkie","Chan", email="elkie.chan@cruk.cam.ac.uk", role =c("ctb")), person("Christopher", "Smith", email="christopher.smith@cruk.cam.ac.uk", role = c("ctb")), person("Tomer", "Kaplan", email="tomer.kaplan@cruk.cam.ac.uk", role = c("ctb")), person("Florian", "Markowetz", email="florian.markowetz@cruk.cam.ac.uk", role = c("ctb")), person("Nitzan","Rosenfeld", email="nitzan.rosenfeld@cruk.cam.ac.uk", role =c("ctb"))) Description: cfDNA fragments carry important features for building cancer sample classification ML models, such as fragment size, and fragment end motif etc. Analyzing and visualizing fragment size metrics, as well as other biological features in a curated, standardized, scalable, well-documented, and reproducible way might be time intensive. This package intends to resolve these problems and simplify the process. It offers two sets of functions for cfDNA feature characterization and visualization. Depends: R (>= 4.1.0), magrittr (>= 1.5.0) Imports: tibble, GenomicAlignments, IRanges, plyranges, GenomeInfoDb, GenomicRanges, BiocGenerics, stats, utils, dplyr (>= 0.8.3), stringr (>= 1.4.0), quantmod (>= 0.4), ggplot2 (>= 3.2.1), Rsamtools (>= 2.4.0), rlang (>= 0.4.0), BSgenome.Hsapiens.UCSC.hg38, BSgenome.Hsapiens.UCSC.hg19, BSgenome.Hsapiens.NCBI.GRCh38 Suggests: scales, ggpubr, knitr (>= 1.23), rmarkdown (>= 1.14), devtools (>= 2.3.0), BiocStyle, testthat License: GPL-3 Encoding: UTF-8 RoxygenNote: 7.2.2 VignetteBuilder: knitr URL: https://github.com/hw538/cfDNAPro BugRePORTS: https://github.com/hw538/cfDNAPro/issues BiocType: Software Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:56:37 UTC RemoteUrl: https://github.com/bioc/cfDNAPro RemoteRef: RELEASE_3_23 RemoteSha: 354165aeb30d65ba570cfb2f52da302347f6463f NeedsCompilation: no Packaged: 2026-10-06 10:05:48 UTC; root Author: Haichao Wang [aut, cre], Hui Zhao [ctb], Elkie Chan [ctb], Christopher Smith [ctb], Tomer Kaplan [ctb], Florian Markowetz [ctb], Nitzan Rosenfeld [ctb] Maintainer: Haichao Wang