Package 'cfToolsData'

Title: ExperimentHub data for the cfTools package
Description: The cfToolsData package supplies the data for the cfTools package. It contains two pre-trained deep neural network (DNN) models for the cfSort function. Additionally, it includes the shape parameters of beta distribution characterizing methylation markers associated with four tumor types for the CancerDetector function, as well as the parameters characterizing methylation markers specific to 29 primary human tissue types for the cfDeconvolve function.
Authors: Ran Hu [aut, cre] (ORCID: <https://orcid.org/0000-0002-0563-8957>), Shuo Li [aut] (ORCID: <https://orcid.org/0000-0002-1960-6016>), Xianghong Jasmine Zhou [aut] (ORCID: <https://orcid.org/0000-0002-4522-7490>), Wenyuan Li [aut] (ORCID: <https://orcid.org/0000-0002-5029-8525>)
Maintainer: Ran Hu <[email protected]>
License: file LICENSE
Version: 1.10.0
Built: 2026-10-10 11:16:42 UTC
Source: https://github.com/bioc/cfToolsData

Help Index


ExperimentHub datasets for the cfTools package

Description

The cfToolsData package supplies data for the cfTools package. It contains two pre-trained deep neural network (DNN) models for the cfSort function. Additionally, it includes the shape parameters of beta distribution characterizing methylation markers associated with four cancer types and 29 primary human tissue types as example files for the CancerDetector and the cfDeconvolve function.

For more information, see https://doi.org/10.1038/s41467-022-32995-6 and https://doi.org/10.1073/pnas.2305236120.

Value

Downloads and caches '.txt.gz' or HDF5-formatted '.h5' files.

Author(s)

Ran Hu


Parameters of COAD markers

Description

The shape parameters of beta distribution characterizing methylation markers associated with colon adenocarcinoma (COAD)

Value

Downloads and caches a '.txt.gz' file.

Examples

COADMarkerParams <- COAD.tumorMarkerParams.hg19()
COADMarkerParams

Model DNN1

Description

The 1st deep neural network in cfSort.

Value

Downloads and caches a '.h5' file in HDF5 format.

Examples

modelDNN1 <- DNN1()
modelDNN1

Model DNN2

Description

The 2nd deep neural network in cfSort.

Value

Downloads and caches a '.h5' file in HDF5 format.

Examples

modelDNN2 <- DNN2()
modelDNN2

Parameters of LIHC markers

Description

The shape parameters of beta distribution characterizing methylation markers associated with liver hepatocellular carcinoma (LIHC)

Value

Downloads and caches a '.txt.gz' file.

Examples

LIHCMarkerParams <- LIHC.tumorMarkerParams.hg19()
LIHCMarkerParams

Parameters of lung cancer markers

Description

The shape parameters of beta distribution characterizing methylation markers associated with lung cancer

Value

Downloads and caches a '.txt.gz' file.

Examples

LUNGMarkerParams <- LUNG.tumorMarkerParams.hg19()
LUNGMarkerParams

Parameters of STAD markers

Description

The shape parameters of beta distribution characterizing methylation markers associated with stomach adenocarcinoma (STAD)

Value

Downloads and caches a '.txt.gz' file.

Examples

STADMarkerParams <- STAD.tumorMarkerParams.hg19()
STADMarkerParams

Annotation of tissue markers

Description

The annotation of strategies used to identify tissue markers.

Value

Downloads and caches a '.txt.gz' file.

Examples

tissueMarkerAnnot <- tissueMarkerParams.annot()
tissueMarkerAnnot

Parameters of tissue markers

Description

The shape parameters of beta distribution characterizing methylation markers specific to 29 primary human tissue types

Value

Downloads and caches a '.txt.gz' file.

Examples

tissueMarkerParams <- tissueMarkerParams.hg19()
tissueMarkerParams