Version: 2.16.0 Text: Transition to Kai Wang as maintainer. Version: 2.10.0 Text: Added data required for proxReg: enhancers.dnase_thurman.0, gene.enh.desc, spline.log_dtss.90ENCODE Version: 2.10.0 Text: Added mouse enhancer data for proxReg; added hg19 enhancer data to chipenrich.data Version: 2.8.0 Text: Added Comparative Toxicogenomics Database for mm9 Version: 2.4.0 Text: Updated locus definitions based on TxDb 3.4.0 and OrgDb 3.5.0 packages Version: 2.4.0 Text: Remove gene expression and EHMN gene sets. Version: 2.2.0 Text: Updated GO gene sets based on org.Db and GO.db 3.4.2 packages. Version: 2.2.0 Text: Added gene sets from MSigDB. Specifically Hallmark, Immunologic Signatures, MicroRNA targets, Oncogenic Signatures, and Transcription Factor targets for human. Version: 2.2.0 Text: Added Comparative Toxicogenomics Database gene sets for human. Version: 2.2.0 Text: Updated BioCarta, DrugBank, KEGG, and pfam gene sets for human. Version: 2.2.0 Text: Use BioGrid for human protein interactions instead of MiMi. Version: 2.2.0 Text: Remove mirBase and MiMi based gene sets. Version: 2.0.0 Category: NEW FEATURES Text: Added locus definitions for danRer10 (zebrafish), dm6, hg38, rn5, and rn6. Version: 2.0.0 Category: NEW FEATURES Text: All genomes have the following locus definitions: nearest_tss, nearest_gene, exon, intron, 1kb, 5kb, 10kb, 1kb_outside_upstream, 5kb_outside_upstream, 10kb_outside_upstream, 1kb_outside, 5kb_outside, and 10kb_outside. Version: 2.0.0 Category: NEW FEATURES Text: Added Reactome genesets for fly. Version: 2.0.0 Category: NEW FEATURES Text: Added GO and Reactome genesets for zebrafish. Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: GO and Reactome gene sets are based on the most up to date data from orgDb and Reactome, respectively. Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Changes to LocusDefinition class. Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: mcols for granges representation are 'gene_id' (formerly names) and 'symbol' Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Including gene symbols in the LocusDefinition allows removal of genes.*.RData Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Changes to tss.*.RData objects Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Now GRanges instead of a list with different representations. Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Use roxygen2 to build LocusDefinition, GeneSet, and tss documentation. Version: 2.0.0 Category: SIGNIFICANT USER-LEVEL CHANGES Text: Documentation for rebuilt objects in data/ include packages / sources used and version numbers. Version: 2.0.0 Category: SIGNIFICANT BACKEND CHANGES Text: Use data-raw/ to store code for building LocusDefinition, GeneSet, and tss objects that are stored as RData in data/. Version: 2.0.0 Category: SIGNIFICANT BACKEND CHANGES Text: Use data-raw/ to store any data needed for GeneSet objects. Version: 2.0.0 Category: DEPRECATED AND DEFUNCT Text: Removed the chrom2iranges representation from the LocusDefinition class. Version: 2.0.0 Category: BUG FIXES Text: Version: 1.2.0 Category: NEW FEATURES Text: Support for D. melanogaster genome (dm3) Version: 1.2.0 Category: NEW FEATURES Text: All genomes (dm3, hg19, mm9, mm10, and rn4) have the following locus definitions Version: 1.2.0 Category: NEW FEATURES Text: 1kb, 5kb, 10kb, >10kb, introns, exons, nearest_gene, and nearest_tss Version: 1.2.0 Category: NEW FEATURES Text: New example histone data set, peaks_H3K4me3_GM12878, based on hg19. Version: 1.2.0 Category: NEW FEATURES Text: New gene sets from Reactome for human, mouse, and rat. Version: 1.0 Category: PKG FEATURES Text: Supporting package containing data for use with the chipenrich package. Version: 1.0 Category: PKG FEATURES Text: Contains genesets for many databases including Biocarta, KEGG, OMIM, etc. Version: 1.0 Category: PKG FEATURES Text: Contains gene locus definitions (for assigning ChIP-seq peaks to genes) Version: 1.0 Category: PKG FEATURES Text: Contains mappability estimates for each gene locus definition Version: 1.0 Category: PKG FEATURES Text: Example ChIP-seq peak datasets Version: 0.99.3 Category: NEW FEATURES Text: Locus definitions for mm10 Version: 0.99.3 Category: BUG FIXES Text: Mouse mappability gene IDs were incorrect for some locus definitions and would cause a crash if used Version: 0.99.2 Category: USER-VISIBLE CHANGES Text: Updated to switch from Depends: to Imports: per bioconductor guidelines Version: 0.99.2 Category: USER-VISIBLE CHANGES Text: Updated license to GPL-3 Version: 0.99.2 Category: USER-VISIBLE CHANGES Text: Updated NEWS format per bioconductor guidelines Version: 0.99.2 Category: USER-VISIBLE CHANGES Text: Made several man pages runnable (removed donttest) Version: 0.99.1 Category: USER-VISIBLE CHANGES Text: Minor updates to documentation and DESCRIPTION Version: 0.99.0 Category: NEW FEATURES Text: Initial submission to bioconductor Version: 0.4.4 Category: USER-VISIBLE CHANGES Text: Updated 1kb/5kb locus definitions using new code Version: 0.4.3 Category: BUG FIXES Text: Fixed 1kb/5kb locus definitions (they were previously the same by accident!) Version: 0.4.2 Category: NEW FEATURES Text: Added support for rat (locus definitions, gene sets from GO and ConceptGen/LRpath) Version: 0.4.2 Category: BUG FIXES Text: Fixed nearest gene mappabilities for human and mouse Version: 0.4.1 Category: USER-VISIBLE CHANGES Text: Changed TSSs to come from knownGenes instead of refFlat Version: 0.4 Category: USER-VISIBLE CHANGES Text: Changed format of TSS object to include strand information Version: 0.4 Category: USER-VISIBLE CHANGES Text: Updated cytoband to use Bioconductor (org.Mm.eg.db) for mouse