Package: crisprBase Version: 1.16.0 Date: 2025-10-27 Title: Base functions and classes for CRISPR gRNA design Authors@R: person("Jean-Philippe", "Fortin", email = "fortin946@gmail.com", role = c("aut", "cre")) Depends: utils, methods, R (>= 4.1) Imports: BiocGenerics, Biostrings, GenomicRanges, graphics, IRanges, S4Vectors, stringr Suggests: BiocStyle, knitr, rmarkdown, testthat biocViews: CRISPR, FunctionalGenomics Description: Provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported. License: MIT + file LICENSE Encoding: UTF-8 RoxygenNote: 7.3.3 VignetteBuilder: knitr BugReports: https://github.com/crisprVerse/crisprBase/issues URL: https://github.com/crisprVerse/crisprBase Collate: 'AllGenerics.R' 'rebase.R' 'Nuclease-class.R' 'Nickase-class.R' 'CrisprNuclease-class.R' 'CrisprNickase-class.R' 'BaseEditor-class.R' 'arithmetics.R' 'data.R' 'utils.R' 'converters.R' 'annotateMismatches.R' LazyData: true Config/pak/sysreqs: libicu-dev zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:57:37 UTC RemoteUrl: https://github.com/bioc/crisprBase RemoteRef: RELEASE_3_23 RemoteSha: 00f5ba957ff3ff7b5b69591c332dc36395d9c44f NeedsCompilation: no Packaged: 2026-10-10 13:12:44 UTC; root Author: Jean-Philippe Fortin [aut, cre] Maintainer: Jean-Philippe Fortin