Package: generegulation Title: Finding Candidate Binding Sites for Known Transcription Factors via Sequence Matching Version: 1.36.0 Date: 2017-09-05 Authors@R: c(person(role=c("aut", "cre"), "Bioconductor Package Maintainer", email = "maintainer@bioconductor.org")) Description: The binding of transcription factor proteins (TFs) to DNA promoter regions upstream of gene transcription start sites (TSSs) is one of the most important mechanisms by which gene expression, and thus many cellular processes, are controlled. Though in recent years many new kinds of data have become available for identifying transcription factor binding sites (TFBSs) -- ChIP-seq and DNase I hypersensitivity regions among them -- sequence matching continues to play an important role. In this workflow we demonstrate Bioconductor techniques for finding candidate TF binding sites in DNA sequence using the model organism Saccharomyces cerevisiae. The methods demonstrated here apply equally well to other organisms. Depends: R (>= 3.3.0), BSgenome.Scerevisiae.UCSC.sacCer3, Biostrings, GenomicFeatures, MotifDb, S4Vectors, TxDb.Scerevisiae.UCSC.sacCer3.sgdGene, motifStack, org.Sc.sgd.db, seqLogo License: Artistic-2.0 Encoding: UTF-8 VignetteBuilder: knitr biocViews: Workflow, EpigeneticsWorkflow Suggests: knitr, rmarkdown, BiocStyle NeedsCompilation: no URL: https://www.bioconductor.org/help/workflows/generegulation/ Config/pak/sysreqs: cmake make libgsl0-dev libbz2-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:40:31 UTC RemoteUrl: https://github.com/bioc/generegulation RemoteRef: RELEASE_3_23 RemoteSha: bccda2d62b18f04fbab0a4692ea14f44a27751a8 Packaged: 2026-10-09 12:22:01 UTC; root Author: Bioconductor Package Maintainer [aut, cre] Maintainer: Bioconductor Package Maintainer