Package: genomicInstability Version: 1.18.0 Date: 2020-02-21 Title: Genomic Instability estimation for scRNA-Seq Authors@R: c(person("Mariano", "Alvarez", role=c("aut", "cre"), email="reef103@gmail.com"), person("Pasquale", "Laise", role="aut", email="plaise@darwinhealth.com"), person("DarwinHealth", role="cph")) Depends: R (>= 4.1.0), checkmate Suggests: SingleCellExperiment, ExperimentHub, pROC Imports: mixtools, SummarizedExperiment Description: This package contain functions to run genomic instability analysis (GIA) from scRNA-Seq data. GIA estimates the association between gene expression and genomic location of the coding genes. It uses the aREA algorithm to quantify the enrichment of sets of contiguous genes (loci-blocks) on the gene expression profiles and estimates the Genomic Instability Score (GIS) for each analyzed cell. License: file LICENSE biocViews: SystemsBiology, GeneExpression, SingleCell BiocType: Software URL: https://github.com/DarwinHealth/genomicInstability BugReports: https://github.com/DarwinHealth/genomicInstability Encoding: UTF-8 ARoxygenNote: 7.1.1 RoxygenNote: 7.1.1 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:56:43 UTC RemoteUrl: https://github.com/bioc/genomicInstability RemoteRef: RELEASE_3_23 RemoteSha: 5df93470d2833edf0865738455a6306ce1bc01af NeedsCompilation: no Packaged: 2026-07-18 05:43:36 UTC; root Author: Mariano Alvarez [aut, cre], Pasquale Laise [aut], DarwinHealth [cph] Maintainer: Mariano Alvarez