Package: h5vc 2.46.0

Paul Theodor Pyl

h5vc: Managing alignment tallies using a hdf5 backend

This package contains functions to interact with tally data from NGS experiments that is stored in HDF5 files.

Authors:Paul Theodor Pyl

h5vc_2.46.0.tar.gz
h5vc_2.46.0.zip(r-4.7)h5vc_2.46.0.zip(r-4.6)h5vc_2.46.0.zip(r-4.5)
h5vc_2.46.0.tgz(r-4.6-x86_64)h5vc_2.46.0.tgz(r-4.6-arm64)h5vc_2.46.0.tgz(r-4.5-x86_64)h5vc_2.46.0.tgz(r-4.5-arm64)
h5vc_2.46.0.tar.gz(r-4.7-arm64)h5vc_2.46.0.tar.gz(r-4.7-x86_64)h5vc_2.46.0.tar.gz(r-4.6-arm64)h5vc_2.46.0.tar.gz(r-4.6-x86_64)
manual.pdf |manual.html✨
card.svg |card.png
h5vc/json (API)

# Install 'h5vc' in R:

install.packages('h5vc', repos = c('https://bioc-release.r-universe.dev', 'https://cloud.r-project.org'))

Uses libs:

curl– Easy-to-use client-side URL transfer library
bzip2– High-quality block-sorting file compressor library
xz-utils– XZ-format compression library
zlib– Compression library
c++– GNU Standard C++ Library v3

Datasets:

bases - Mutation spectrum analyses

On BioConductor:h5vc-2.47.0(bioc 3.24)h5vc-2.46.0(bioc 3.23)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

curl bzip2 xz-utils zlib cpp

3.60 score 4 scripts 494 downloads 1 mentions 36 exports 77 dependencies

Last updated from:c99f423530 (on RELEASE_3_23). Checks:1 ERROR, 11 NOTE, 1 OK, 1 FAIL. Indexed: no.

Target	Result	Time
bioc-checks	ERROR	296
linux-devel-arm64	NOTE	368
linux-devel-x86_64	NOTE	449
source / vignettes	OK	524
linux-release-arm64	NOTE	360
linux-release-x86_64	NOTE	416
macos-release-arm64	NOTE	208
macos-release-x86_64	NOTE	506
macos-oldrel-arm64	NOTE	249
macos-oldrel-x86_64	NOTE	446
windows-devel	NOTE	647
windows-release	NOTE	666
windows-oldrel	NOTE	727
wasm-release	FAIL	257

Exports:applyTallies bases batchTallies batchTallyParam binGenome binnedAFs binnedCoverage callVariantsPaired callVariantsPairedFisher callVariantsSingle collectTallies defineBlocks encodeDNAString formatGenomicPosition geom_h5vc getChromSize getSampleData h5dapply h5readBlock mergeTallies mergeTallyFiles mismatchPlot mutationSpectrum plotMutationSpectrum prepareForHDF5 prepareTallyFile rerunBatchTallies resizeCohort setSampleData tallyBAM tallyRanges tallyRangesBatch tallyRangesToFile vcConfParams writeReference writeToTallyFile

Dependencies:abind askpass backports base64enc BatchJobs BBmisc BH BiocGenerics biocmake BiocParallel Biostrings bit bit64 bitops blob brew cachem checkmate cli codetools cpp11 crayon curl data.table DBI digest dir.expiry farver fastmap filelock formatR futile.logger futile.options generics GenomeInfoDb GenomicRanges ggplot2 glue gridExtra gtable h5vcData httr IRanges isoband jsonlite labeling lambda.r lifecycle memoise mime openssl pkgconfig plyr R6 RColorBrewer Rcpp reshape rhdf5 rhdf5filters Rhdf5lib Rhtslib rlang Rsamtools RSQLite S4Vectors S7 scales sendmailR Seqinfo snow stringi sys UCSC.utils vctrs viridisLite withr XVector

Building a minimal genome browser with h5vc and shiny

Rendered fromh5vc.simple.genome.browser.Rmdusingknitr::rmarkdownon May 24 2026.

Last update: 2019-02-12
Started: 2013-09-24

h5vc -- Tour

Rendered fromh5vc.tour.Rmdusingknitr::rmarkdownon May 24 2026.

Last update: 2025-01-22
Started: 2014-01-28

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Managing alignment tallies using a hdf5 backend	h5vc-package h5vc
Preparing the results of tallyBAM for writing to an HDF5 tally file	applyTallies
Tallying bam files in parallel using 'BatchJobs' on high performance compute clusters (HPC)	batchTallies batchTallyParam collectTallies rerunBatchTallies
Function for binning a genome.	binGenome
Estimate allelic frequency distributions in bins along the genome	binnedAFs
Variant calling	callDeletionsPaired callVariantsPaired vcConfParams
Paired variant calling using fisher tests	callVariantsPairedFisher
Single sample variant calling	callVariantsSingle
Coverage analysis	binnedCoverage
geom_h5vc	geom_h5vc
Reading and writing sample data from / to a tally file	getSampleData setSampleData
h5dapply	h5dapply h5dapply,GRanges-method h5dapply,IRanges-method h5dapply,numeric-method
h5readBlock	h5readBlock
helper functions	defineBlocks encodeDNAString formatGenomicPosition getChromSize
Merging the prepared results from multiple bam file tallies into one block that can be written to the HDF5 tally file	mergeTallies
Merging multiple tally files into one	mergeTallyFiles
mismatchPlot	mismatchPlot
Mutation spectrum analyses	bases mutationSpectrum variantCalls
Plotting a mutation spectrum	plotMutationSpectrum
Preparing the results of tallyBAM for writing to an HDF5 tally file	prepareForHDF5
prepareTallyFile	prepareTallyFile resizeCohort
tallyBAM	tallyBAM
Tallying function with a 'GRanges' interface.	tallyRanges tallyRangesBatch tallyRangesToFile
Filling the Reference dataset in a tally file from a DNAString	writeReference
Writing data to an HDF5 tally file	writeToTallyFile