# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "hummingbird" in publications use:' type: software title: 'hummingbird: Bayesian Hidden Markov Model for the detection of differentially methylated regions' version: 1.22.0 doi: 10.32614/CRAN.package.hummingbird abstract: A package for detecting differential methylation. It exploits a Bayesian hidden Markov model that incorporates location dependence among genomic loci, unlike most existing methods that assume independence among observations. Bayesian priors are applied to permit information sharing across an entire chromosome for improved power of detection. The direct output of our software package is the best sequence of methylation states, eliminating the use of a subjective, and most of the time an arbitrary, threshold of p-value for determining significance. At last, our methodology does not require replication in either or both of the two comparison groups. authors: - family-names: Adam given-names: Eleni email: eadam002@odu.edu - family-names: Ji given-names: Tieming - family-names: Ranjan given-names: Desh repository: https://bioc-release.r-universe.dev commit: b1a90a419c449cbf335144eebdc3952a2c4a4d1a date-released: '2026-04-28' contact: - family-names: Adam given-names: Eleni email: eadam002@odu.edu