Package: linkSet Title: Base Classes for Storing Genomic Link Data Version: 1.2.0 Authors@R: c(person("Gilbert", "Han", , "GilbertHan1011@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0000-0293-2467"))) Description: Provides a comprehensive framework for representing, analyzing, and visualizing genomic interactions, particularly focusing on gene-enhancer relationships. The package extends the GenomicRanges infrastructure to handle paired genomic regions with specialized methods for chromatin interaction data from Hi-C, Promoter Capture Hi-C (PCHi-C), and single-cell ATAC-seq experiments. Key features include conversion from common interaction formats, annotation of promoters and enhancers, distance-based analyses, interaction strength metrics, statistical modeling using CHiCANE methodology, and tailored visualization tools. The package aims to standardize the representation of genomic interaction data while providing domain-specific functions not available in general genomic interaction packages. License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Depends: GenomicRanges, S4Vectors, R (>= 4.5.0) Imports: methods, IRanges, GenomeInfoDb, BiocGenerics, Organism.dplyr, InteractionSet, ggplot2, patchwork, scales, foreach, iterators, stats, rlang, MASS, data.table, DBI, doParallel, AnnotationDbi Suggests: knitr, rmarkdown, testthat, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Mm.eg.db, org.Hs.eg.db, GenomicFeatures, GenomicInteractions, gamlss, gamlss.tr, BiocStyle, rtracklayer Collate: class.R AllGenerics.R getset.R methods.R annotate.R distance.R formatConverter.R linkSet-package.R GRange_method.R test_helper.R visualization.R count.R statical.R data.R biocViews: Software, HiC, DataRepresentation, Sequencing, SingleCell, Coverage URL: https://github.com/GilbertHan1011/linkSet, https://gilberthan1011.github.io/linkSet BugReports: https://github.com/GilbertHan1011/linkSet/issues/new VignetteBuilder: knitr Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 13:05:16 UTC RemoteUrl: https://github.com/bioc/linkSet RemoteRef: RELEASE_3_23 RemoteSha: ebca282075fcf9c317c7e1bf47c6253af8f9e742 NeedsCompilation: no Packaged: 2026-09-22 07:57:10 UTC; root Author: Gilbert Han [aut, cre] (ORCID: ) Maintainer: Gilbert Han