Package 'scanMiRData'

Title: miRNA Affinity models for the scanMiR package
Description: This package contains companion data to the scanMiR package. It contains `KdModel` (miRNA 12-mer binding affinity models) collections corresponding to all human, mouse and rat mirbase miRNAs. See the scanMiR package for details.
Authors: Pierre-Luc Germain [cre, aut] (ORCID: <https://orcid.org/0000-0003-3418-4218>), Michael Soutschek [aut], Fridolin Gross [aut]
Maintainer: Pierre-Luc Germain <[email protected]>
License: GPL-3
Version: 1.18.0
Built: 2026-10-10 11:15:38 UTC
Source: https://github.com/bioc/scanMiRData

Help Index


getKdModels

Description

Returns a collection of miRNA KdModels for the requested species. Note that by default, low-confidence miRNAs are not returned (see 'categories').

Usage

getKdModels(species = c("hsa", "mmu", "rno"), categories = NULL)

Arguments

species

Either "hsa" (human), "mmu" (mouse) or "rno" (rat)

categories

The categories of miRNAs to return. Any combination of "Low-confidence", "Poorly conserved", "Conserved across mammals", "Conserved across vertebrates". If NULL (default), all categories are returned. miRNAs with NA as conservation are not returned unless 'categories==NULL'.

Value

An object of class KdModelList

Examples

mods <- getKdModels("rno")
summary(mods)

KdModelList for human miRNAs

Description

A list of binding affinity models (KdModel) for human ('hsa'), mouse ('mmu'), or rat ('rno') miRbase 21.1 miRNAs. These represent the miRNA 12-mer binding affinities predicted using the CNN from McGeary, Lin et al. (2019).

Value

a KdModelList list.


KdModelList for mouse miRNAs

Description

A list of binding affinity models (KdModel) for mouse miRbase 21.1 miRNAs. These represent the miRNA 12-mer binding affinities predicted using the CNN from McGeary, Lin et al. (2019).

Value

a KdModelList list.


KdModelList for rat miRNAs

Description

A list of binding affinity models (KdModel) for rat miRbase 21.1 miRNAs. These represent the miRNA 12-mer binding affinities predicted using the CNN from McGeary, Lin et al. (2019).

Value

a KdModelList list.