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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "sevenC" in publications use:'
type: software
license: GPL-3.0-only
title: 'sevenC: Computational Chromosome Conformation Capture by Correlation of ChIP-seq
  at CTCF motifs'
version: 1.32.0
doi: 10.1186/s12864-019-6088-0
identifiers:
- type: doi
  value: 10.32614/CRAN.package.sevenC
abstract: Chromatin looping is an essential feature of eukaryotic genomes and can
  bring regulatory sequences, such as enhancers or transcription factor binding sites,
  in the close physical proximity of regulated target genes. Here, we provide sevenC,
  an R package that uses protein binding signals from ChIP-seq and sequence motif
  information to predict chromatin looping events. Cross-linking of proteins that
  bind close to loop anchors result in ChIP-seq signals at both anchor loci. These
  signals are used at CTCF motif pairs together with their distance and orientation
  to each other to predict whether they interact or not. The resulting chromatin loops
  might be used to associate enhancers or transcription factor binding sites (e.g.,
  ChIP-seq peaks) to regulated target genes.
authors:
- family-names: Ibn-Salem
  given-names: Jonas
  email: jonas.ibn-salem@tron-mainz.de
preferred-citation:
  type: article
  title: '7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq
    at CTCF motifs'
  authors:
  - family-names: Ibn-Salem
    given-names: Jonas
    email: jonas.ibn-salem@tron-mainz.de
  - family-names: Andrade-Navarro
    given-names: Miguel A.
  year: '2019'
  journal: BMC Genomics
  doi: 10.1186/s12864-019-6088-0
  url: https://doi.org/10.1186/s12864-019-6088-0
  start: 20, 777
repository: https://bioc-release.r-universe.dev
repository-code: https://github.com/ibn-salem/sevenC
commit: e6eb6a9b83aea34e3792fea2e77185af24a2b444
url: https://github.com/ibn-salem/sevenC
date-released: '2026-04-28'
contact:
- family-names: Ibn-Salem
  given-names: Jonas
  email: jonas.ibn-salem@tron-mainz.de