Package: spatzie 1.18.0

Jennifer Hammelman

spatzie: Identification of enriched motif pairs from chromatin interaction data

Identifies motifs that are significantly co-enriched from enhancer-promoter interaction data. While enhancer-promoter annotation is commonly used to define groups of interaction anchors, spatzie also supports co-enrichment analysis between preprocessed interaction anchors. Supports BEDPE interaction data derived from genome-wide assays such as HiC, ChIA-PET, and HiChIP. Can also be used to look for differentially enriched motif pairs between two interaction experiments.

Authors:Jennifer Hammelman [aut, cre, cph], Konstantin Krismer [aut], David Gifford [ths, cph]

spatzie_1.18.0.tar.gz
spatzie_1.18.0.zip(r-4.7)spatzie_1.18.0.zip(r-4.6)spatzie_1.18.0.zip(r-4.5)
spatzie_1.18.0.tgz(r-4.6-any)spatzie_1.18.0.tgz(r-4.5-any)
spatzie_1.18.0.tar.gz(r-4.7-any)spatzie_1.18.0.tar.gz(r-4.6-any)
spatzie_1.18.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
spatzie/json (API)
NEWS

# Install 'spatzie' in R:
install.packages('spatzie', repos = c('https://bioc-release.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:

On CRAN:

Conda:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

dna3dstructuregeneregulationpeakdetectionepigeneticsfunctionalgenomicsclassificationhictranscription

3.60 score 10 scripts 233 downloads 8 exports 154 dependencies

Last updated from:c15b967076 (on RELEASE_3_23). Checks:1 WARNING, 7 ERROR, 2 OK. Indexed: no.

TargetResultTimeFilesSyslog
bioc-checksWARNING444
linux-devel-x86_64ERROR702
source / vignettesOK456
linux-release-x86_64ERROR645
macos-release-arm64ERROR421
macos-oldrel-arm64ERROR281
windows-develERROR531
windows-releaseERROR637
windows-oldrelERROR574
wasm-releaseOK295

Exports:anchor_pair_enrichcompare_motif_pairsfilter_motifsfilter_pair_motifsfind_ep_coenrichmentget_specific_interactionsplot_motif_occurrencescan_motifs

Dependencies:abindAnnotationDbiAnnotationFilteraskpassbackportsbase64encBHBiobaseBiocFileCacheBiocGenericsBiocIOBiocParallelbiomaRtBiostringsbiovizBasebitbit64bitopsblobBSgenomebslibcachemcaToolscheckmatecigarillocliclustercodetoolscolorspacecpp11crayoncurldata.tableDBIdbplyrDelayedArraydeldirdichromatdigestDirichletMultinomialdplyrensembldbevaluatefarverfastmapfilelockfontawesomeforeignformatRFormulafsfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomicAlignmentsGenomicFeaturesGenomicInteractionsGenomicRangesggplot2gluegridExtragtablegtoolsGvizhighrHmischmshtmlTablehtmltoolshtmlwidgetshttrhttr2igraphInteractionSetinterpIRangesisobandjpegjquerylibjsonliteKEGGRESTknitrlabelinglambda.rlatticelatticeExtralazyevallifecyclemagrittrMASSMatrixMatrixGenericsmatrixStatsmemoisemimemotifmatchrnnetopensslpillarpkgconfigpngprettyunitsprogressProtGenericspurrrpwalignR6rappdirsRColorBrewerRcppRcppArmadilloRcppEigenRCurlrestfulrRhtslibrjsonrlangrmarkdownrpartRsamtoolsRSQLiterstudioapirtracklayerS4ArraysS4VectorsS7sassscalesSeqinfoseqLogosnowSparseArraystringistringrSummarizedExperimentsysTFBSToolsTFMPvaluetibbletidyrtidyselecttinytexUCSC.utilsutf8VariantAnnotationvctrsviridisLitewithrxfunXMLxml2XVectoryaml

YY1 ChIA-PET motif analysis (single call)

Rendered fromsingle-call.Rmdusingknitr::rmarkdownon May 28 2026.

Last update: 2025-07-23
Started: 2021-05-20

YY1 ChIA-PET motif analysis (step-by-step)

Rendered fromindividual-steps.Rmdusingknitr::rmarkdownon May 28 2026.

Last update: 2025-07-23
Started: 2021-05-20

Readme and manuals

Help Manual

Help pageTopics
Determine enriched motifs in anchorsanchor_pair_enrich
spatzie count correlation data setanchor_pair_example_count
spatzie match association data setanchor_pair_example_match
spatzie score correlation data setanchor_pair_example_score
Compare pairs of motifs between two interaction datasetscompare_motif_pairs
compare_motif_pairs examplecompare_pairs_example
Filter motifs based on occurrence within interaction datafilter_motifs
Filter significant motif interactionsfilter_pair_motifs
spatzie score correlation filtered data setfilter_pairs_example
Find co-enriched motif pairs in enhancer-promoter interactionsfind_ep_coenrichment
Get interactions that contain a specific motif pairget_specific_interactions
K562 Enhancer - Promoter Interactions Data Setint_data_k562
MSLCL Enhancer - Promoter Interactions Data Setint_data_mslcl
Mouse YY1 Enhancer - Promoter Interactions Data Setint_data_yy1
Mouse YY1 Enhancer - Promoter Interactions Data Setinteractions_yy1
Mouse YY1 Enhancer - Promoter Interactions Data Set - YY1 enhancersinteractions_yy1_enhancer
Mouse YY1 Enhancer - Promoter Interactions Data Set - YY1 enhancers/promotersinteractions_yy1_ep
Mouse YY1 Enhancer - Promoter Interactions Data Set - YY1 promotersinteractions_yy1_promoter
Plot motif occurrenceplot_motif_occurrence
Interactions scanned for motifs - interactionData objectscan_interactions_example
Interactions with motifs filtered for significance - interactionData objectscan_interactions_example_filtered
Scans interaction file for motif instancesscan_motifs
spatziespatzie