Package: toppgene Title: Gene List Enrichment Analysis using the ToppGene Suite Version: 1.0.2 Authors@R: c( person("Pariksheet Nanda", email = "pan79@pitt.edu", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-9726-4552")), person("Jason Shoemaker", email = "jason.shoemaker@pitt.edu", role = "fnd", comment = c(ORCID = "0000-0003-3315-7103"))) Description: The ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. Although the ToppCluster web application provides convenient graphical access to the ToppGene Suite, the OpenAPI 3.0 compliant interface of ToppGene is better suited for automation and reproducibility. This package includes Bioconductor class interfaces and biological examples. BiocType: Software biocViews: Clustering, GeneExpression, GeneSetEnrichment, Genetics, MotifDiscovery, Network, NetworkEnrichment, Pathways, Pharmacogenetics, Proteomics, Software, ThirdPartyClient URL: https://github.com/ImmuSystems-lab/toppgene BugReports: https://github.com/ImmuSystems-lab/toppgene/issues Depends: R (>= 4.5.0) Encoding: UTF-8 License: GPL (>= 3) Imports: BiocFileCache, httr2, IRanges, jsonlite, methods, purrr, readr, S4Vectors, xml2, yaml Suggests: BiocStyle, DFplyr (>= 1.5.0), knitr, rmarkdown, testthat (>= 3.0.0) RoxygenNote: 7.3.3 VignetteBuilder: knitr Config/testthat/edition: 3 Config/testthat/parallel: true Config/pak/sysreqs: libicu-dev libxml2-dev libssl-dev libx11-dev Repository: Bioconductor 3.23 Date/Publication: 2026-08-03 16:03:15 UTC RemoteUrl: https://github.com/bioc/toppgene RemoteRef: RELEASE_3_23 RemoteSha: 0e37fc846ebb5d3ef95f41334e884c1523450a27 NeedsCompilation: no Packaged: 2026-10-06 13:12:10 UTC; root Author: Pariksheet Nanda [aut, cre] (ORCID: ), Jason Shoemaker [fnd] (ORCID: ) Maintainer: Pariksheet Nanda