Package: variants Title: Annotating Genomic Variants Version: 1.36.0 Date: 2025-07-18 Authors@R: c( person("Valerie", "Obenchain", role = "aut"), person("Martin", "Morgan", role = "ctb"), person( "Bioconductor Package Maintainer", role="cre", email = "maintainer@bioconductor.org" )) Description: Read and write VCF files. Identify structural location of variants and compute amino acid coding changes for non-synonymous variants. Use SIFT and PolyPhen database packages to predict consequence of amino acid coding changes. Depends: R (>= 3.3.0), GenomeInfoDb, VariantAnnotation, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene, BSgenome.Hsapiens.UCSC.hg19, PolyPhen.Hsapiens.dbSNP131 License: Artistic-2.0 Encoding: UTF-8 VignetteBuilder: knitr biocViews: ImmunoOncologyWorkflow, AnnotationWorkflow, Workflow Suggests: knitr, rmarkdown, BiocStyle NeedsCompilation: no URL: https://bioconductor.org/help/workflows/variants/ Config/pak/sysreqs: make libbz2-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: Bioconductor 3.23 Date/Publication: 2026-04-28 12:43:22 UTC RemoteUrl: https://github.com/bioc/variants RemoteRef: RELEASE_3_23 RemoteSha: 97d5b9ac31f1bdcecb925f6c9e4a51dd6b12d044 Packaged: 2026-10-04 17:14:53 UTC; root Author: Valerie Obenchain [aut], Martin Morgan [ctb], Bioconductor Package Maintainer [cre] Maintainer: Bioconductor Package Maintainer