Package: metapone 1.18.0

Tianwei Yu

metapone: Conducts pathway test of metabolomics data using a weighted permutation test

The package conducts pathway testing from untargetted metabolomics data. It requires the user to supply feature-level test results, from case-control testing, regression, or other suitable feature-level tests for the study design. Weights are given to metabolic features based on how many metabolites they could potentially match to. The package can combine positive and negative mode results in pathway tests.

Authors:Leqi Tian [aut], Tianwei Yu [aut], Tianwei Yu [cre]

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manual.pdf |manual.html
card.svg |card.png
metapone/json (API)

# Install 'metapone' in R:
install.packages('metapone', repos = c('https://bioc-release.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:
  • hmdbCompMZ - The m/z values of common adduct ions of HMDB metaboites
  • hmdbCompMZ.metapone - The m/z values of common adduct ions of metapone metaboites
  • neg - Example negative mode data from the Metabolome Atlas of the Aging Mouse Brain
  • pa - Pathway-metabolite match file.
  • pos - Example positive mode data from the Metabolome Atlas of the Aging Mouse Brain

On BioConductor:metapone-1.19.0(bioc 3.24)metapone-1.18.0(bioc 3.23)

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

technologymassspectrometrymetabolomicspathways

4.00 score 9 scripts 322 downloads 5 exports 42 dependencies

Last updated from:40e2f17287 (on RELEASE_3_23). Checks:1 WARNING, 9 OK. Indexed: no.

TargetResultTimeFilesSyslog
bioc-checksWARNING155
linux-devel-x86_64OK298
source / vignettesOK618
linux-release-x86_64OK322
macos-release-arm64OK219
macos-oldrel-arm64OK236
windows-develOK340
windows-releaseOK351
windows-oldrelOK354
wasm-releaseOK123

Exports:bbplot1dbbplot2dftablemetaponeptable

Dependencies:BHBiocParallelclicodetoolscommonmarkcowplotcpp11data.tabledotCall64farverfastmatchfdrtoolfgseafieldsformatRfutile.loggerfutile.optionsggplot2ggrepelgluegtableisobandlabelinglambda.rlatticelifecyclelitedownmapsmarkdownMatrixR6RColorBrewerRcpprlangS7scalessnowspamvctrsviridisLitewithrxfun

METAbolic pathway testing combining POsitive and NEgative mode data (metapone)

Rendered frommetapone.Rmdusingknitr::rmarkdownon May 29 2026.

Last update: 2022-06-04
Started: 2022-01-17